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Models

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Mice

hPSGL-1(2)

Strain Name：C57BL/6Smoc-Selplgem2(hSELPLG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210026
Validation Data：Presence

The endogenous mice Selplg gene was completely or partially replaced by human SELPLG gene via CRISPR/Cas9 mediated recombination.

Mice

Pvalb-2A-mCherry

Strain Name：C57BL/6Smoc-Pvalbem(2A-mCherry)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220177
Validation Data：Absence

2A-mCherry expression cassette was knocked into the Pvalb gene stop codon site.

Mice

Bag3-Flox

Strain Name：C57BL/6Smoc-Bag3em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-2101856
Validation Data：Absence

These mice carry loxP sites flanking exon 4 of Bag3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Bag3 gene.

Mice

Col1a1-IRES-CreERT2

Strain Name：C57BL/6Smoc-Col1a1em(IRES-CreERT2)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225031
Validation Data：Presence

IRES-CreERT2 expression cassette was knocked into the Col1a1 gene. The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

Lepr-KO

Strain Name：C57BL/6Smoc-Leprem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190663
Validation Data：Absence

Exon 5 of Lepr gene was deleted to generate Lepr knockout mice.

Mice

Il10-KO(BALB/c)

Strain Name：BALB/cAnSmoc-Il10em4Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200637
Validation Data：Absence

Exon 1-5 of Il10 gene was deleted to generate Il10 knockout mice.

Mice

hIL7R

Strain Name：C57BL/6Smoc-Il7rem1(hIL7R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210027
Validation Data：Absence

The endogenous mice Il7r gene was completely or partially replaced by human IL7R gene via ESC targeting.

Mice

Il17f-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il17fem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00031
Validation Data：Absence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il17f.

Mice

hPD-1/hPD-L1/hTIM3

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Havcr2em1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200264
Validation Data：Absence

hTIM3（NM-HU-00054）,hPD-1（NM-HU-00015）,hPD-L1（NM-HU-00062）were crossed together to generate hPD-1/hPD-L1/hTIM3 mice

Mice

hIDO1

Strain Name：B6;129S-Ido1em1(hIDO1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00061
Validation Data：Absence

The endogenous mouse Ido1 gene was replaced by human IDO1 gene.

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