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Models

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Mice

R26-CAG-LSL-hHER2-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-HER2-luciferase-EGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190008
Validation Data：Absence

A SA-2xpolyA-CAG-LSL-HER2-IRES-Luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the HER2 protein.

Mice

Foxp3-IRES-tdTomato-2A-Cre

Strain Name：C57BL/6Smoc-Foxp3em3(IRES-tdTomato-2A-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190119
Validation Data：Presence

A IRES-tdTomato-2A-Cre expression cassette was knocked into the Foxp3 gene stop codon site. This strain is useful in studying regulatory T cell in autoimmunity, especially in type 1 diabetes.

Mice

Car4-DreERT2

Strain Name：C57BL/6Smoc-Car4em1(DreERT2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200193
Validation Data：Absence

A DreERT2-Wpre-pA expression cassette was knocked into the Car4 gene start codon site.

Mice

hCXCL13

Strain Name：C57BL/6Smoc-Cxcl13em1(hCXCL13)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225079
Validation Data：Presence

The endogenous mouse Cxcl13 gene was replaced by human CXCL13 gene.

Mice

hIL6ST

Strain Name：C57BL/6Smoc-Il6stem1(hIL6ST)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204980
Validation Data：Absence

The endogenous mice Il6st gene was replaced by human IL6ST gene.

Mice

Ly6a-2A-Cre

Strain Name：C57BL/6Smoc-Ly6aem1(2A-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190028
Validation Data：Presence

A 2A-iCre expression cassette was knocked into the Ly6a gene stop codon site.

Mice

Ncr1-2A-CreERT2

Strain Name：C57BL/6Smoc-Ncr1em4(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200004
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

Piezo1-CreERT2

Strain Name：C57BL/6Smoc-Piezo1tm2(CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18048
Validation Data：Absence

This tamoxifen-inducing Piezo1-CreERT2 tool mouse model was established by inserting a 2A-CreERT2 co-expression cassette into the Piezo1 gene stop codon site .

Mice

Krt5-2A-CreERT2

Strain Name：C57BL/6Smoc-Krt5em1(2A-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190016
Validation Data：Absence

The 2A-CreERT2 cassette is inserted before 3'UTR region of Krt5 gene.

Mice

hMELTF

Strain Name：C57BL/6Smoc-Meltfem(hMELTF)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215011
Validation Data：Presence

The endogenous mouse Meltf gene was replaced by human MELTF gene.

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