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Models

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Mice

hIL18BP

Strain Name：C57BL/6Smoc-Il18bpem1(hIL18BP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210039
Validation Data：Presence

The endogenous mice Il18bp gene was replaced by human IL18BP gene.

Mice

Siglecf-DreERT2

Strain Name：C57BL/6Smoc-Siglecfem1(kozak-DreER-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200202
Validation Data：Absence

A kozak-DreER-WPRE-pA expression cassette was knocked into the Siglecf gene start codon site.

Mice

Ncr1-IRES-Cre

Strain Name：C57BL/6Smoc-Ncr1em(IRES-Cre)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225008
Validation Data：Presence

IRES-Cre expression cassette was knocked into the Ncr1 gene .

Mice

Tlr5-CreERT2

Strain Name：C57BL/6Smoc-Tlr5em1(CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215033
Validation Data：Presence

CreERT2 expression cassette was knocked into the Tlr5 gene.

Mice

hHER3

Strain Name：C57BL/6Smoc-Erbb3em1(hERBB3)Smoc
Strain State：Developing | Cat. NO.：NM-HU-200234
Validation Data：Absence

The endogenous mice Erbb3 gene was replaced by human HER3 gene.

Mice

hCXCR6

Strain Name：C57BL/6Smoc-Cxcr6em(hCXCR6)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215001
Validation Data：Presence

The endogenous mice Cxcr6 gene was replaced by human CXCR6 gene.

Mice

Tie1-2A-Cre

Strain Name：C57BL/6Smoc-Tie1em1(2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18023
Validation Data：Absence

A 2A-Cre coexpression cassette is inserted befor the stop codon of mouse Tie1 gene via homologous recombination to establish a tamoxifen inducible Tie1-Cre tool stain. This strain can be used to knockout target gene in Tie1+ cells when crossed with mice which carry loxp sites flanking target gene.

Mice

hIL31

Strain Name：C57BL/6Smoc-Il31em2(IL31)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200008
Validation Data：Presence

The endogenous mouse Il31 gene was replaced by human IL31 gene.

Mice

Csf2rb2-2A-Cre

Strain Name：C57BL/6Smoc-Csf2rb2em1(2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210001
Validation Data：Presence

2A-Cre expression cassette was knocked into the Csf2rb2 gene. Csf2rb2 is also known as colony stimulating factor 2 receptor. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. The gene product has been involved in the modulation of memory.

Mice

hAPOE4

Strain Name：C57BL/6Smoc-Apoeem2(hAPOE4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190002
Validation Data：Presence

This APOE4 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE4 corresponding sequence by homologous recombination.

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