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Models

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Mice

hIL2RA/hIL2RB/hIL2RG

Strain Name：C57BL/6Smoc-Il2raem1(hIL2RA)Il2rgem1(IL2RG)Il2rbem1(hIL2RB)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210414
Validation Data：Presence

hIL2RA(NM-HU-190064) was crossed with hIL2RG/hILRB(NM-HU-210354) to generate hIL2RA/hIL2RB/hIL2RG mice.

Mice

hCD93

Strain Name：C57BL/6Smoc-Cd93em1(hCD93)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215065
Validation Data：Presence

The endogenous mouse Cd93 gene was replaced by human CD93 gene.

Mice

Pax8-Cre

Strain Name：C57BL/6Smoc-Pax8em1(Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200151
Validation Data：Presence

A Cre-WPRE-polyA expression cassette was knocked into the Pax8 gene start codon site.

Mice

Pax7-2A-DreERT2

Strain Name：C57BL/6Smoc-Pax7em1(2A-DreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190124
Validation Data：Presence

A 2A-DreERT2 expression cassette was knocked into the Pax7 gene stop codon site.

Mice

Itgax-2A-DreERT2

Strain Name：C57BL/6Smoc-Itgaxem1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190032
Validation Data：Absence

A 2A-DreERT2 expression cassette was knocked into the Itgax gene stop codon site.

Mice

Lep-KO

Strain Name：B6;129S-Leptm1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-00034
Validation Data：Presence

Exon 2 was replaced by Neo cassette.

Mice

R26-CAG-LNL-CaMPARI

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LNL-CaMPARI)-NSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00090
Validation Data：Absence

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven CaMPARI gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination.

Mice

hIl5

Strain Name：C57BL/6Smoc-Il5em3(hIL5)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190001
Validation Data：Presence

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.

Mice

hCTLA-4/hCCR8(BALB/c)

Strain Name：BALB/cAnSmoc-Ccr8em1(hCCR8)Ctla4em1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220050
Validation Data：Absence

hCTLA4(BALB/c)(NM-HU-190078) was crossed with hCCR8(BALB/c)(NM-HU-2000048) to generate hCTLA4/hCCR8(BALB/c) mice．

Mice

hCD40/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Cd40em1(hCD40)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210406
Validation Data：Absence

hPD-1/hPD-L1(NM-HU-00100) was crossed with hCD40（NM-HU-00076）to generate hCD40/hPD-1/hPD-L1 mice

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