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Models

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Mice

H11-CAG-LSL-Mycn-IRES-EGFP

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-HAtag-Mycn-IRES-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190084
Validation Data：Absence

These mice harbor a CAG-LSL-HA tag-Mycn-IRES-EGFP cassette in the lgs2 locus generated by homologous recombination.

Mice

Wnt1-Dre

Strain Name：C57BL/6Smoc-Wnt1em1(Dre-Wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200176
Validation Data：Presence

A Dre-Wpre-polyA expression cassette was knocked into the Wnt1 gene start codon site. Wnt1 gene is involved in stem cell poliferation in multiple systems, including the hematopoietic system and the embryonic nervous system. This strain may be useful for studying central nervous system development. When crossed with a strain carrying a gene flanked by rox sites, the flanked gene will be removed in cells expressing dre.

Mice

hPSMA

Strain Name：C57BL/6Smoc-Folh1em1(hPSMA-Wpre-PA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200240
Validation Data：Presence

The endogenous mice Folh1 gene was replaced by human PSMA gene.

Mice

Fah-KO

Strain Name：C57BL/6Smoc-Fahem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191202
Validation Data：Absence

Partial exon 8 of Fah gene was deleted to generate Fah knockout mice.

Mice

hCXCR3

Strain Name：C57BL/6Smoc-Cxcr3em1(hCXCR3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200219
Validation Data：Presence

The endogenous mouse Cxcr3 gene was completely or partially replaced by human CXCR3 gene via ESC targeting.

Mice

Il18-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il18em1(Luc-eGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00032
Validation Data：Presence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il18.

Mice

hIL17A/hIL17F

Strain Name：C57BL/6Smoc-Il17aem1(hIL17A)Il17fem2(hIL17F)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200281
Validation Data：Presence

The endogenous mouse Il17a&Il17f genes were replaced by human IL17A&IL17F gene.

Mice

hIGFBP2

Strain Name：C57BL/6Smoc-Igfbp2em1(hIGFBP2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225085
Validation Data：Absence

The endogenous mouse Igfbp2 gene was replaced by human IGFBP2 gene.

Mice

hTNFR2/hIL2RA

Strain Name：C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Il2ratm1(hIL2RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210408
Validation Data：Absence

hTNFRSF1B(NM-HU-190010) was crossed with hIL2RA(NM-HU-190064) to generate hTNFRSF1B/hIL2RA mice.

Mice

A1bg-Flox

Strain Name：C57BL/6Smoc-A1bgem1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD
Validation Data：Absence

These mice carry loxP sites flanking target exons of A1bg gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A1bg gene.

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