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Models

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Mice

hCD3E/hPD-L1

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E)Cd274em1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210449
Validation Data：Presence

hCD3E(NM-HU-00114) was crossed with hPD-L1(NM-HU-00062) to generate hCD3E/hPD-L1 mice

Mice

hIFNGR2

Strain Name：C57BL/6Smoc-Ifngr2em(hIFNGR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215010
Validation Data：Presence

The endogenous mouse Ifngr2 gene was replaced by human IFNGR2 gene.

Mice

hCTLA-4/h4-1BB(2)

Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4)Tnfrsf9em2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210355
Validation Data：Absence

hCTLA4(NM-HU-00014) was crossed with h4-1BB(2)(NM-HU-190077）to generate hCTLA4/h4-1BB(2) mice.

Mice

R26-hCD46-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-hCD46-IRES-tdTomato-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190087
Validation Data：Presence

These mice harbor a SA-human CD46-IRES-tdTomato-polyA cassette in the Rosa26 locus generated by homologous recombination.

Mice

hIGHG4

Strain Name：C57BL/6Smoc-Ighg1em1(hIGHG4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225092
Validation Data：Presence

The endogenous mouse Ighg1 gene was replaced by human IGHG4 gene.

Mice

hSPP1

Strain Name：C57BL/6Smoc-Spp1em1(hSPP1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225037
Validation Data：Presence

The endogenous mouse Spp1 gene was replaced by human SPP1 gene.

Mice

hGCGR

Strain Name：C57BL/6Smoc-Gcgrem(hGCGR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215004
Validation Data：Presence

The endogenous mice Gcgr gene was replaced by human GCGR gene.

Mice

hCD55

Strain Name：C57BL/6Smoc-Cd55em(hCD55)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215008
Validation Data：Presence

The endogenous mouse Cd55 gene was replaced by human CD55 gene.

Mice

Foxp3-V5-AviTag-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Foxp3em1(V5-AviTag-IRES-luci-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18034
Validation Data：Absence

A V5-AviTag-IRES-luci-2A-tdTomato expression cassette was inserted before the stop codon TGA of mouse Foxp3 gene to establish a multi-labeled knockin model with V5, Avi, luciferase and tdTomato fluorescent protein.

Mice

hPD-L1/hCD27(2)

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Cd27tm3(hCD27)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200274
Validation Data：Absence

hPD-L1(NM-HU-00062) was crossed with hCD27(2)(NM-HU-190035)to generate hPD-L1/hCD27(2) mice.While hPD-L1/hCD27 (Stock No.NM-HU-18023) have been pulled from shelves for some reasons.

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