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Models

About 43,966 results
Mice

hIL33

Strain Name：C57BL/6Smoc-Il33tm2(hIL33)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000069
Validation Data：Presence

The endogenous mouse Il33 gene was replaced by human IL33 gene.

Mice

hCD96

Strain Name：C57BL/6Smoc-Cd96em2(hCD96)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000059
Validation Data：Presence

The endogenous mouse Cd96 gene was replaced by human CD96 gene.

Mice

hPD-1/hLAG3

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Lag3em1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00101
Validation Data：Absence

hPD-1(NM-HU-00015) was crossed with hLAG3(NM-HU-00049)to generate hPD-1/hLAG3 mice

Mice

hRSPO1

Strain Name：C57BL/6Smoc-Rspo1em1(hRSPO1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225041
Validation Data：Presence

The endogenous mouse Rspo1 gene was replaced by human RSPO1 gene.

Mice

hICOS/hICOSL

Strain Name：C57BL/6Smoc-Icoslem1(hICOSLG) Icosem1(hICOS)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18018
Validation Data：Presence

This ICOS and ICOSL double knockin strain is established by crossing ICOS-HU and ICOSL-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

Foxn1-IRES-Cre

Strain Name：C57BL/6Smoc-Foxn1em1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200106
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Foxn1 gene stop codon site. The protein encoded by Foxn1 (forkhead box N1) gene is part of the forkhead family or transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in thymic epithelial cell and keratinocytes.

Mice

Scgb1a1-IRES-CreERT2

Strain Name：C57BL/6Smoc-Scgb1a1em1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200129
Validation Data：Presence

A IRES-CreERT2 expression cassette was knocked into the Scgb1a1 gene stop codon site.

Mice

hSLAMF7

Strain Name：C57BL/6Smoc-Slamf7em(hSLAMF7)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18028
Validation Data：Absence

The endogenous mouse Slamf7 gene was replaced by human SLAMF7 gene .

Mice

hIL21R

Strain Name：C57BL/6Smoc-Il21rem1(hIL21R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210031
Validation Data：Presence

The endogenous mice Il21r gene was completely or partially replaced by human IL21R gene via ESC targeting.

Mice

C4b-KO

Strain Name：C57BL/6Smoc-C4bem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190761
Validation Data：Absence

Exon 3 of C4b gene was deleted to generate C4b knockout mice.

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