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Models

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Mice

Cck-IRES-Cre

Strain Name:C57BL/6Smoc-Cckem1(IRES-iCre-PolyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200131
Validation Data:Presence

A IRES-iCre-PolyA expression cassette was knocked into the Cck gene stop codon site.

Mice

Gad2-IRES-Cre

Strain Name:C57BL/6Smoc-Gad2em1(IRES-iCre-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200078
Validation Data:Presence

A IRES-iCre-pA expression cassette was knocked into the Gad2 gene stop codon site.

Mice

hCXCR4

Strain Name:C57BL/6Smoc-Cxcr4em1(hCXCR4)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000081
Validation Data:Presence

The endogenous mouse Cxcr4 gene was replaced by human CXCR4 gene.

Mice

hCYP2D6

Strain Name:C57BL/6Smoc-Cyp2dem(hCYP2D6)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-215024
Validation Data:Absence

The endogenous mouse Cyp2d22 gene was replaced by human CYP2D6 gene.

Mice

Angptl6-KO

Strain Name:C57BL/6Smoc-Angptl6em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-201240
Validation Data:Absence

Exon 3 of Angptl6 gene was deleted to generate Angptl6 knockout mice.

Mice

R26-LSL-hIL15-Flag-IRES-EGFP

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220130
Validation Data:Absence

CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA expression cassette was knocked into the the Rosa26 locus

Mice

hIL5-Tg(NMG,2)

Strain Name:NOD.Cg-PrkdcscidIl2rgem2Tg(hIL5)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220131
Validation Data:Presence

These transgenic mice carry humanized IL5.While hIL5-Tg(NMG)(Stock No.NM-KI-215005) mice function similarly to hIL5-Tg(NMG)(2) mice, for more detailed information please contact our technical advisor.

Mice

hSOST

Strain Name:C57BL/6Smoc-Sostem1(hSOST)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200251
Validation Data:Presence

The endogenous mice Sost gene was replaced by human SOST gene. While hSOST(2)(Stock No.NM-HU-215021) mice function similarly to hSOST mice, for more detailed information please contact our technical advisor.

Mice

Lyz2-2A-CreERT2

Strain Name:C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18018
Validation Data:Presence

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

hSERPINA1

Strain Name:C57BL/6Smoc-Serpina1eem1(hSERPINA1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225055
Validation Data:Presence

The endogenous mouse Serpina1e gene was replaced by human SERPINA1 gene.

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