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Models

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Mice

F8-KO

Strain Name:B6.129S-F8tm1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-00012
Validation Data:Presence

F8-KO mice (Stock No.NM-KO-00012)carry a knockout allele derived from the targeted deletion of exon 16-19. While F8-KO(2) mice (Stock No.NM-KO-200608) carrying the exon 1-26 deletion.

Mice

hPVRL2

Strain Name:C57BL/6Smoc-Nectin2tm1(hNECTIN2)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000084
Validation Data:Presence

The endogenous mouse Nectin2 gene was replaced by human PVRL2 gene.

Mice

hCSF2RB

Strain Name:C57BL/6Smoc-Csf2rbem1(hCSF2RB)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225078
Validation Data:Presence

The endogenous mouse Csf2rb gene was replaced by human CSF2RB gene.

Mice

Casp8-Flox

Strain Name:C57BL/6Smoc-Casp8em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-190003
Validation Data:Absence

These Casp8 flox mice possess loxP sites flanking exons 4. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

hCD40/hCD40L

Strain Name:C57BL/6Smoc-CD40em2(hCD40)Cd40lgem1(hCD40L)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200268
Validation Data:Presence

hCD40(NM-HU-00076)was crossed with hCD40L(NM-HU-2000033)to generate hCD40/hCD40L mice

Mice

hTNFR2/hPD-1/hPD-L1

Strain Name:C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220041
Validation Data:Absence

hTNFRSF1B(NM-HU-190010),hPD-1(NM-HU-00015) and hPD-L1(NM-HU-00062) were crossed together to generate hTNFRSF1B/hPD-1/hPD-L1 mice.

Mice

Cd68-IRES-Cre

Strain Name:C57BL/6Smoc-Cd68em1(IRES-Cre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200161
Validation Data:Absence

A IRES-Cre expression cassette was knocked into the Cd68 gene stop codon site.

Mice

hHGF

Strain Name:C57BL/6Smoc-Hgfem1(hHGF)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200235
Validation Data:Absence

The endogenous mice Hgf gene was replaced by human HGF gene.

Mice

hPD-L1/hCD73(2)

Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Nt5eem2(NT5E)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210356
Validation Data:Absence

hPD-L1(NM-HU-00062) was crossed with hCD73(2)(NM-HU-200009) to generate hPD-L1/hCD73(2) mice.

Mice

hHER2

Strain Name:C57BL/6Smoc-Erbb2em1(hERBB2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200115
Validation Data:Presence

The endogenous mouse Erbb2 gene was replaced by human ERBB2 gene.

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