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Mice

hPD-1/hOX40

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Tnfrsf4em3(hTNFRSF4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00108
Validation Data：Absence

hPD-1（NM-HU-00015）was crossed with hOX40（NM-HU-00041）to generate hPD-1/hOX40.

Mice

hTIMD4

Strain Name：C57BL/6Smoc-Timd4em1(hTIMD4)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215055
Validation Data：Absence

The endogenous mouse Timd4 gene was replaced by human TIMD4 gene.

Mice

Gad1-2A-eGFP

Strain Name：C57BL/6Smoc-Gad1em(2A-eGFP)Smoc
Strain State：Developing | Cat. NO.：NM-KI-220179
Validation Data：Absence

2A-eGFP expression cassette was knocked into the Gad1 gene stop codon site.

Mice

hPD-1/hTIGIT

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1) Tigitem1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00104
Validation Data：Absence

hPD-1(NM-HU-00015) was crossed with hTIGIT(NM-HU-00053) to generate hPD-1/hTIGIT.

Mice

Emx1-IRES-Cre

Strain Name：C57BL/6Smoc-emx1em1(IRES-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200149
Validation Data：Presence

A IRES-Cre expression cassette was knocked into the Emx1 gene stop codon site.

Mice

Brca1-Flox

Strain Name：C57BL/6Smoc-Brca1tm1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-18007
Validation Data：Absence

These Brca1 flox mice possess loxP sites flanking exons 5 . When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Il17a-Cre

Strain Name：C57BL/6Smoc-Il17aem1(iCre-polyA(SV40))Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200137
Validation Data：Presence

A iCre-polyA expression cassette was knocked into the Il17a gene start codon site. This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying autoimmune inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis.

Mice

hPD-1/hPD-L1/hIDO1

Strain Name：C57BL/6Smoc-Ido1tm1(hIDO1)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00120
Validation Data：Absence

hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062) were crossed with hIDO1(NM-HU-00061) to generate hPD-1/hPD-L1/hIDO1.

Mice

Ifngr1/Ifnar1-KO

Strain Name：C57BL/6Smoc-Ifngr1em1Ifnar1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190425
Validation Data：Presence

This Ifngr1 and Ifnar1 double knockout strain is established by crossing Ifngr1-KO and Ifnar1-KO mice together.

Mice

hANGPTL3(3)

Strain Name：C57BL/6Smoc-Angptl3em2(hANGPTL3)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210037
Validation Data：Presence

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(4)(Stock No.NM-HU-210036) mice function similarly to hANGPTL3(3) mice, for more detailed information please contact our technical advisor.

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