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Models

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Mice

hCD33

Strain Name：C57BL/6Smoc-Cd33em3(CD33)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200002
Validation Data：Presence

The endogenous mouse Cd33 gene was replaced by human CD33 gene .

Mice

hGPR75

Strain Name：C57BL/6Smoc-Gpr75em1(hGPR75)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215056
Validation Data：Presence

The endogenous mouse Gpr75 gene was replaced by human GPR75 gene.

Mice

hPDGFRA

Strain Name：C57BL/6Smoc-Pdgfraem1(hPDGFRA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200250
Validation Data：Absence

The endogenous mice Pdgfra gene was replaced by human PDGFRA gene.

Mice

Cd68-IRES-CreERT2

Strain Name：C57BL/6Smoc-Cd68em1(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200162
Validation Data：Absence

A IRES-CreERT2 expression cassette was knocked into the Cd68 gene stop codon site.

Mice

hIL1B(BALB/c)

Strain Name：BALB/cAnSmoc-Il1bem3(hIL1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220017
Validation Data：Presence

The endogenous mouse Il1b gene was replaced by human IL1B gene.

Mice

Aldh7a1-KO

Strain Name：C57BL/6Smoc-Aldh7a1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-253410
Validation Data：Absence

The exon 6 of Aldh7a1 gene was deleted to generate Aldh7a1 knockout mouse.

Mice

Arg1-KO

Strain Name：C57BL/6Smoc-Arg1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200629
Validation Data：Absence

Exon 3 of Arg1 gene was deleted to generate Arg1 knockout mice.

Mice

Drd1-2A-CreERT2

Strain Name：C57BL/6Smoc-Drd1em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18016
Validation Data：Presence

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Drd1 gene via homologous recombination to establish a tamoxifen inducible Drd1-CreERT2 tool stain. This strain can be used to knockout target gene in Drd1+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

Wt1-CreERT2

Strain Name：C57BL/6Smoc-Wt1em1(CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200127
Validation Data：Presence

A CreERT2-WPRE-pA expression cassette was knocked into the Wt1 gene start codon site.

Mice

Wt1-GFPCre

Strain Name：C57BL/6Smoc-Wt1em1(GFPCre-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200128
Validation Data：Presence

A GFPCre-WPRE-pA expression cassette was knocked into the Wt1 gene start codon site.

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