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Models

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Mice

hFCGR2B

Strain Name：C57BL/6Smoc-Fcgr2bem3(hFCGR2B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000010
Validation Data：Presence

The endogenous mouse Fcgr2b gene was replaced by human FCGR2B gene.

Mice

hCXCR2

Strain Name：C57BL/6Smoc-Cxcr2em2(hCXCR2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-18025
Validation Data：Absence

The endogenous mouse Cxcr2 gene was replaced by human CXCR2 gene.

Mice

hPD-L1/hOX40

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Tnfrsf4em1(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00111
Validation Data：Absence

hPD-L1（NM-HU-00062）was crossed with hOX40（NM-HU-00041）to generate hPD-L1/hOX40.

Mice

Apc-Flox

Strain Name：C57BL/6Smoc-Apctm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200013
Validation Data：Absence

These mice carry loxP sites flanking exon 15 of Apc gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Apc gene.

Mice

Il12b-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il12bem1(Luc-eGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00025
Validation Data：Absence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.

Mice

hOX40(2)

Strain Name：C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00078
Validation Data：Presence

The exon1-5 and partial exon6 of endogenous mouse Tnfrsf4(Ox40) gene was replaced by the corresponding region of human TNFRSF4(OX40) gene. While hOX40(Stock No.NM-HU-00041) mice function similarly to hOX40(2) mice,for more detailed information please contact our technical advisor.

Mice

hTNFR2/hPD-1

Strain Name：C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Pdcd1em1(hPDCD1) /Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210407
Validation Data：Absence

hTNFRSF1B(NM-HU-190010) was crossed with hPD-1（NM-HU-00015）to generate hTNFRSF1B/hPD-1 mice

Mice

Trp53-Flox

Strain Name：C57BL/6Smoc-Trp53tm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-18005
Validation Data：Absence

These Trp53 flox mice possess loxP sites flanking exons 5-7 via ESC targeting. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

hPD-L1/hSTING

Strain Name：C57BL/6Smoc-Tmem173em1(hTMem173)Cd274em1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000105
Validation Data：Absence

hPD-L1(NM-HU-00062) was crossed with hSTING(NM-HU-190036) to generate hPD-L1/hSTING.

Mice

hPVR

Strain Name：C57BL/6Smoc-Pvrem1(hPVR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190012
Validation Data：Presence

The endogenous mouse Pvr gene was replaced by human PVR gene.

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