Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Immunodeficient NMG Mice
Strain Name:C57BL/6Smoc-Albem1(IRES-iCre-WPRE-pA)Smoc Strain State:Developing | Cat. NO.:NM-KI-200075 Validation Data:Absence
A IRES-iCre-WPRE-pA expression cassette was knocked into the Alb gene stop codon site.
Strain Name:C57BL/6Smoc-Il12atm3(hIL12A)/Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000056 Validation Data:Presence
The endogenous mouse Il12a gene was replaced by human IL12A gene.
Strain Name:C57BL/6Smoc-Igs2em1(CAG-LSL-ZsGreen-wpre-pA-CAG-RSR-tdTomato-wpre-pA)Smoc Strain State:Repository Live | Cat. NO.:NM-KI-200319 Validation Data:Absence
A CAG-LSL-ZsGreen-wpre-pA-CAG-RSR-tdTomato-wpre-pA expression cassette was knocked into the H11 locus.
Strain Name:C57BL/6Smoc-Tigitem3(hTIGIT)Tnfrsf1bem2(hTNFRSF1B)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210371 Validation Data:Absence
hTIGIT(3)(NM-HU-200244) was crossed with hTNFRSF1B(NM-HU-190010)to generate hTIGIT(3)/hTNFRSF1B mice
Strain Name:C57BL/6Smoc-Appem1Smoc Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190444 Validation Data:Absence
exon 3 of App gene was deleted to generate App knockout mice.
Strain Name:C57BL/6Smoc-Cd28em2(hCD28)Cd38em2(CD38)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210350 Validation Data:Absence
hCD38(NM-HU-190059) was crossed with hCD28(NM-HU-190011) to generate hCD28/hCD38 mice.
Strain Name:C57BL/6Smoc-Tmem119em2(P2A-CreERT2)Smoc Strain State:Repository Live | Cat. NO.:NM-KI-200234 Validation Data:Presence
A P2A-CreERT2 expression cassette was knocked into the Tmem119 gene stop codon site.
Strain Name:C57BL/6Smoc-Clec4fem1(IRES-DTRGFP)Smoc Strain State:Repository Live | Cat. NO.:NM-KI-200070 Validation Data:Absence
A IRES-DTRGFP expression cassette was knocked into the Clec4f gene stop codon site.
Strain Name:C57BL/6Smoc-Drd2em1Smoc Strain State:Repository Live | Cat. NO.:NM-KO-190265 Validation Data:Absence
This Drd2 knockout mouse model was generated by knocking out the exon 3 region of the Drd2.
Strain Name:C57BL/6Smoc-Cd8aem(T2A-tdTomato-P2A-Luciferase)1Smoc Strain State:Repository Live | Cat. NO.:NM-KI-225025 Validation Data:Presence
T2A-tdTomato-P2A-Luciferase expression cassette was knocked into the Cd8a gene .
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