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Models

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Mice

hCD22

Strain Name：C57BL/6Smoc-Cd22em2(hCD22)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000014
Validation Data：Presence

The endogenous mouse Cd22 gene was replaced by human CD22 gene.

Mice

hIL2/hIL2RA/hIL2RB/hIL2RG

Strain Name：C57BL/6Smoc-Il2em3(hIL2)Il2raem1(hIL2RA)Il2rgem1(IL2RG)Il2rbem1(hIL2RB)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210415
Validation Data：Presence

hIL2/hIL2RA(NM-HU-200275) was crossed with hIL2RA/hIL2RB/hIL2RG(NM-HU-210414) to generate hIL2/hIL2RA/hIL2RB/hIL2RG mice.

Mice

Cd8a-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Cd8aem1(V5-IRES-luci-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18030
Validation Data：Presence

A V5-IRES-luci-2A-EGFP expression cassette was inserted before the stop codon TAA of mouse Cd8a gene to establish a multi-labeled knockin model with V5, luciferase and EGFP fluorescent protein.

Mice

hPD-1/hCTLA-4

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00079
Validation Data：Presence

hPD-1(NM-HU-00015) was crossed with hCTLA4(NM-HU-00014)to generate hPD-1/hCTLA4 mice

Mice

R26-CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luc

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luciferase)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200257
Validation Data：Absence

A CAG-LSL-HPV-E6-CAG-LSL-HPV-E7-IRES-Luciferase expression cassette was knocked into the Rosa26 locus.

Mice

hCLEC4C

Strain Name：C57BL/6Smoc-Dppa3em1(hCLEC4C)Smoc
Strain State：Developing | Cat. NO.：NM-HU-225073
Validation Data：Absence

The human CLEC4C gene was knocked in the close location of the Dppa3 gene.

Mice

hTLR8/hPD-1

Strain Name：C57BL/6Smoc-Tlr8em2(TLR8)Pdcd1em1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200276
Validation Data：Absence

hTLR8(NM-HU-190044) was crossed with hPD-1(NM-HU-00015)to generate hTLR8/hPD-1 mice

Mice

hCD80

Strain Name：C57BL/6Smoc-Cd80em1(hCD80) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00074
Validation Data：Presence

The endogenous mouse Cd80 gene was replaced by human CD80 gene .

Mice

hCD27(2)/hFCGR2B

Strain Name：C57BL/6Smoc-Cd27tm3(hCD27)Fcgrt2bem2(hFCGRT2B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210405
Validation Data：Absence

hCD27(2) (NM-HU-190035) was crossed with hFCGR2B (NM-HU-2000010) to generate hCD27(2)/hFCGR2B mice.

Mice

Foxl1-2A-CreERT2

Strain Name：C57BL/6Smoc-Foxl1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00135
Validation Data：Presence

A 2A-CreERT2 coexpression cassette is inserted before the stop codon of mouse Foxl1 gene via homologous recombination to establish a Foxl1-CreERT2 recombinase tool stain. This strain can be used to knockout target gene inFoxl1+ cells after tamoxifen treatment when crossed with flox mice.

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