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Models

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Mice

Ahi1-Flox

Strain Name：B6;129S-Ahi1tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00053
Validation Data：Absence

These mice possess loxP sites on either side of exon 3 the Ahi1 (Abelson helper integration site 1) gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Col2a1-2A-CreERT2

Strain Name：C57BL/6Smoc-Col2a1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18029
Validation Data：Presence

A 2A-CreERT2 expression cassette was knocked into the stop codon of Col2a1 gene to establish a Col2a1-CreERT2 recombinase tool mouse.The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

hVEGFR2

Strain Name：C57BL/6Smoc-Kdrem2(hKDR) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00098
Validation Data：Presence

The endogenous mouse Kdr gene was replaced by human KDR gene .

Mice

hFCRN(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Fcgrtem2(FCGRT)Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-020
Validation Data：Presence

The background of this strain is NMG, and its endogenous Fcgrt gene is replaced with human FCGRT.

Mice

hVSIG4

Strain Name：C57BL/6Smoc-Vsig4em1(hVSIG4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210004
Validation Data：Presence

The endogenous mice Vsig4 gene was replaced by human VSIG4 gene

Mice

Tagln-Cre

Strain Name：C57BL/6Smoc-Taglnem1(Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200144
Validation Data：Presence

A Cre-WPRE-polyA expression cassette was knocked into the Tagln gene start codon site. This gene encodes a smooth muscle cell-specific cytoskeletal protein. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in vascular smooth muscle cells. In mouse models of atherosclerosis, the gene product may be involved in plaque cell and atherosclerotic lesion formation during atherogenesis.

Mice

hCD40/h4-1BB(2)

Strain Name：C57BL/6Smoc-Cd40em1(hCD40)Tnfrsf9em2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200256
Validation Data：Presence

hCD40（NM-HU-00076）was crossed with h4-1BB（NM-HU-190077）to generate hCD40/h4-1BB(2) mice.

Mice

H11-CAG-LSL-mtagBFP2

Strain Name：C57BL/6Smoc-lgs2em1(CAG-LSL-mTagBFP2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190006
Validation Data：Presence

A CAG-LSL-mTagBFP2-3xFLAG-WPRE-polyA cassette was inserted at the mouse H11 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the mTagBFP2-3xFLAG protein.

Mice

Glp1r-IRES-Cre

Strain Name：C57BL/6Smoc-Glp1rem1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200134
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Glp1r gene stop codon site.

Mice

Wls-Flox

Strain Name：B6;129S-Wlstm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00027
Validation Data：Absence

Mice homozygous for this conditional allele possess loxP sites flanking exon 3 of the targeted gene. When bred to mice that express Cre recombinase, the resulting offspring will have the exon encoding this gene deleted in the cre-expressing tissue(s).

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