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Models

About 43,971 results
Mice

Calca-Cre

Strain Name：C57BL/6Smoc-Calcaem1(iCre-2A)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200302
Validation Data：Absence

iCre-2A expression cassette was knocked into the Calca gene start codon site.

Mice

Hopx-2A-DreERT2

Strain Name：C57BL/6Smoc-Hopxem1(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190035
Validation Data：Presence

A 2A-DreERT2 expression cassette was knocked into the Hopx gene stop codon site.

Mice

Akt2-KO

Strain Name：C57BL/6Smoc-Akt2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190742
Validation Data：Absence

Exon 3-4 of Akt2 gene was deleted to generate Akt2 knockout mice.

Mice

hTNFRSF1A

Strain Name：C57BL/6Smoc-Tnfrsf1aem(hTNFRSF1A)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215017
Validation Data：Absence

The endogenous mice Tnfrsf1a gene was replaced by human TNFRSF1A gene.

Mice

hCCR8(2)/hCTLA-4

Strain Name：C57BL/6Smoc-Ccr8em3(hCCR8)Ctla4em1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220074
Validation Data：Presence

hCTLA4 (NM-HU-00014) mice were crossed with hCCR8(2) (NM-HU-2000054) mice to generate hCCR8(2)/hCTLA4 mice．

Mice

hCD20(2)

Strain Name：C57BL/6Smoc-Ms4a1em3(hCD20)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200114
Validation Data：Presence

Extracellular and transmembrane region of the endogenous mouse Ms4a1 gene was replaced by corresponding region of human CD20 gene. While hCD20(Stock No.NM-HU-190068) mice function similarly to hCD20(2) mice,for more detailed information please contact our technical advisor.

Mice

hFCRN

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-hFcRn)Fcgrtem1/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00109
Validation Data：Presence

This FcRn humanized strain is established by mating endogenous mouse Fcgrt gene Knockout mice with R26-hFcRn(FCGRT) Knock-in mice. These FcRn humanized mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations. While hFCRN(2)(Stock No.NM-HU-190070) and hFCRN(3)(Stock No.NM-HU-2000032）mice function similarly to hFCRN mice,for more detailed information please contact our technical advisor.

Mice

hTLR7

Strain Name：C57BL/6Smoc-Tlr7em1(hTLR7)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18027
Validation Data：Presence

The endogenous mouse Tlr7 gene was replaced by humanTLR7 gene.

Mice

hIL6R

Strain Name：C57BL/6Smoc-Il6raem1(hIL6R)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00044
Validation Data：Absence

The endogenous mouse Il6ra gene was replaced by human IL-6R gene .

Mice

hIL17A

Strain Name：C57BL/6Smoc-Il17aem1(hIL17A)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00042
Validation Data：Presence

The endogenous mouse Il17a gene was replaced by human IL17A gene.

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