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Models

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Mice

hTLR9/hOX40

Strain Name：C57BL/6Smoc-Tlr9em1(hTLR9)Tnfrsf4em3(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190024
Validation Data：Absence

This TLR9 and OX40 double knockin strain is established by crossing TLR9-HU and OX40-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hVEGFA(2)

Strain Name：C57BL/6Smoc-Vegfaem1(hVEGFA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204984
Validation Data：Presence

The endogenous mice Vegfa gene was replaced by human VEGFA gene. While hVEGFA(Stock No.NM-HU-2000028) mice function similarly to hVEGFA(2) mice,for more detailed information please contact our technical advisor.

Mice

hCCR8/hCTLA-4

Strain Name：C57BL/6Smoc-Ccr8em1(hCCR8)Ctla4em1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210435
Validation Data：Absence

hCCR8(NM-HU-190053) was crossed with hCTLA4(NM-HU-00014) to generate hCCR8/hCTLA4 mice.

Mice

hSIRPA(2)

Strain Name：C57BL/6Smoc-Sirpaem2(hSIRPA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18015
Validation Data：Presence

The endogenous mouse Sirpa gene was replaced by human SIRPA gene . While hSIRPA (Stock No.NM-HU-00119) have been pulled from shelves for some reasons.

Mice

hCCR8/hPD-1

Strain Name：C57BL/6Smoc-Ccr8em1(hCCR8)Pdcd1em1(hPDCD1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210400
Validation Data：Absence

hCCR8(NM-HU-190053) was crossed with hPD-1(NM-HU-00015) to generate hCCR8/hPD-1 mice.

Mice

Rorc-2A-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Rorcem(T2A-tdTomato-P2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-204991
Validation Data：Absence

T2A-tdTomato-P2A-DTR expression cassette was knocked into the Rorc gene .

Mice

hTTR

Strain Name：C57BL/6Smoc-Ttrem1(hTTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225087
Validation Data：Presence

The endogenous mouse Ttr gene was replaced by human TTR gene.

Mice

Ly6g-2A-CreERT2

Strain Name：C57BL/6Smoc-Ly6gem3(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200218
Validation Data：Presence

A 2A-CreERT2 expression cassette was knocked into the Ly6g gene stop codon region.

Mice

hCSF2

Strain Name：C57BL/6Smoc-Csf2em1(CSF2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190046
Validation Data：Presence

The endogenous mouse Csf2 gene was replaced by human CSF2 gene.

Mice

Agrp-Dre

Strain Name：C57BL/6Smoc-Agrpem(Kozak-Dre-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220331
Validation Data：Absence

Kozak-Dre-WPRE-pA expression cassette was knocked into the Agrp gene start codon site.

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