Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Immunodeficient NMG Mice
Strain Name:C57BL/6Smoc-Cd160em1(CD160)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190057 Validation Data:Absence
The endogenous mouse Cd160 gene was replaced by human CD160 gene.
Strain Name:C57BL/6Smoc-Albem1(Kozak-DreERT2-WPRE-pA)Smoc Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200076 Validation Data:Absence
A Kozak-DreERT2-WPRE-pA expression cassette was knocked into the Alb gene start codon site.
Strain Name:C57BL/6Smoc-Zbtb46em1(IRES-iCre)Smoc Strain State:Repository Live | Cat. NO.:NM-KI-200096 Validation Data:Presence
A IRES-iCre expression cassette was knocked into the Zbtb46 gene stop codon site.
Strain Name:C57BL/6Smoc-Igs2em1(ALB promoter-human ALB-IRES-Luciferase-polyA)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200322 Validation Data:Absence
An ALB promoter-human ALB-IRES-Luciferase-polyA expression cassette was knocked into the H11 locus.
Strain Name:C57BL/6Smoc-EpCAMtm1(hEpCAM)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210032 Validation Data:Presence
The endogenous mice Epcam gene was completely or partially replaced by human EPCAM gene via ESC targeting.
Strain Name:C57BL/6Smoc-Tslptm2(hTSLP)/Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000064 Validation Data:Presence
The endogenous mouse Tslp gene was replaced by human TSLP gene.
Strain Name:C57BL/6Smoc-Cd24atm1(hCD24)Siglecgtm1(hSIGLEC10)Smoc Strain State:Repository Live | Cat. NO.:NM-HU-210367 Validation Data:Presence
hCD24(NM-HU-2000060) was crossed with hSIGLEC10(NM-HU-2000061)to generate hCD24/hSIGLEC10 mice.
Strain Name:C57BL/6Smoc-Tfrctm1(hTFRC)Smoc Strain State:Repository Live | Cat. NO.:NM-HU-215059 Validation Data:Presence
The endogenous mouse Tfrc gene was replaced by human TFRC gene.
Strain Name:C57BL/6Smoc-Abcg2em1Smoc Strain State:Repository Live | Cat. NO.:NM-KO-18013 Validation Data:Absence
Exon3-5 of Abcg2 gene were deleted to generate Abcg2 knockout mice.
Strain Name:C57BL/6Smoc-Sema4dem1(hSEMA4D)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00117 Validation Data:Presence
The endogenous mouse Sema4d gene was replaced by human SEMA4D gene.
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