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Models

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Mice

Arc-CreERT2

Strain Name：C57BL/6Smoc-Arcem1(CreERT2-SV40-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200101
Validation Data：Presence

A CreERT2 expression cassette was knocked into the Arc gene start codon site.

Mice

Cd68-2A-Cre

Strain Name：C57BL/6Smoc-Cd68em5(2A-Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200192
Validation Data：Presence

This Cd68-Cre tool mouse model was established by inserting a 2A-Cre-WPRE-polyA co-expression cassette into the stop codon of Cd68 gene .

Mice

hCD19/hCD3E

Strain Name：C57BL/6Smoc-Cd19em1(hCD19)Cd3eem1(hCD3E)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190027
Validation Data：Presence

This CD19 and CD3E double knockin strain is established by crossing CD19-HU and CD3E-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

Tmem119-2A-DTRGFP

Strain Name：C57BL/6Smoc-Tmem119em4(P2A-DTRGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200235
Validation Data：Absence

A P2A-DTRGFP expression cassette was knocked into the Tmem119 gene stop codon site.

Mice

Axin2-CreERT2

Strain Name：C57BL/6Smoc-Axin2em1(CreERT2-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200109
Validation Data：Presence

A CreERT2-pA expression cassette was knocked into the Axin2 gene start codon site. As Axin2 is an intracellular protein, it is essential for identifying a surface marker for stem cell purification. When these Axin2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Axin2 expressing cells.

Mice

Anxa10-2A-CreERT2

Strain Name：C57BL/6Smoc-Anxa10em1(2A-CreERT2-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200312
Validation Data：Presence

2A-CreERT2-Wpre-pA expression cassette was knocked into the Anxa10 gene stop codon site.

Mice

hCSF1/hCSF1R(2)

Strain Name：C57BL/6Smoc-Csf1em2(CSF1)Csf1rem3(hCSF1R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200273
Validation Data：Absence

hCSF1(NM-HU-190043) was crossed with hCSF1R(NM-HU-190074)to generate hCSF1/hCSF1R(2) mice.

Mice

Ar-Flox

Strain Name：B6;129S-Artm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-00110
Validation Data：Absence

These mice carry loxP sites flanking exon 2 of Ar gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ar gene.

Mice

hCFD

Strain Name：C57BL/6Smoc-Cfdem1(hCFD)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225045
Validation Data：Presence

The endogenous mouse Cfd gene was replaced by human CFD gene.

Mice

Lrat-2A-Cre

Strain Name：C57BL/6Smoc-Lratem1(2A-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190097
Validation Data：Presence

A 2A-Cre expression cassette was knocked into the Lrat gene stop codon site.

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