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Models

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Mice

Cdh5-rtTA-TetO-Cre

Strain Name：B6;129S-Cdh5tm1(rtTA-tetO-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18006
Validation Data：Absence

These mice harbor an M2rtTA-Wpre-polyA-attp-PGK-Neo-polyA-attb-long insulator-tetO-Cre-FRT-Wpre-FRT-polyA-long insulator cassette before ATG of the Cdh5 locus generated homologous recombination.

Mice

CMV-GFP-Tg

Strain Name：B6.Cg-Tg(CMV-GFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-TG-00006
Validation Data：Absence

These mice carry enhanced green fluorescent protein gene driven by CMV promoter.

Mice

CAG-GFP-Tg

Strain Name：B6.Cg-Tg(CAG-GFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-TG-00005
Validation Data：Absence

These mice carry enhanced green fluorescent protein gene driven by CAG promoter.

Mice

hTLR9

Strain Name：C57BL/6Smoc-Tlr9em1(hTLR9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18016
Validation Data：Presence

This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.

Mice

hHBB

Strain Name：C57BL/6Smoc-Hbb-bt&Hbb-bstm1(hHBB)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000080
Validation Data：Presence

The endogenous mouse Hbb-bt and Hbb-bs gene was replaced by human HBB gene.

Mice

hTNFR2

Strain Name：C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190010
Validation Data：Presence

The endogenous mouse Tnfrsf1b gene was replaced by human TNFRSF1B gene.

Mice

hLAG3

Strain Name：B6.129S-Lag3em1(hLAG3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00049
Validation Data：Presence

The endogenous mouse Lag3 gene exon1-7 was replaced by human LAG3 gene extracellular region by homologous recombination.

Mice

Pten-Flox

Strain Name：C57BL/6Smoc-Ptenem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-18004
Validation Data：Absence

These Pten flox mice possess loxP sites flanking exons 5 via CRISPR/Cas mediated recombination. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

hCALCRL

Strain Name：C57BL/6Smoc-Calcrlem1(hCALCRL)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225031
Validation Data：Presence

The endogenous mouse Calcrl gene was replaced by human CALCRL gene.

Mice

Csf1r-IRES-Cre

Strain Name：C57BL/6Smoc-Csf1rem3(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190026
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Csf1r gene stop codon site.

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