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Models

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Mice

hVISTA

Strain Name：C57BL/6Smoc-Vsirem1(hVSIR)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00118
Validation Data：Presence

The exon 2-3 of endogenous mouse Vsir gene was replaced by the exon 2-3 of human VSIR(VISTA) gene.

Mice

Braf-Flox-V600E

Strain Name：C57BL/6Smoc-Brafem1(flox-V600E)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190053
Validation Data：Absence

These mice carry a conditional p.V600E mutation of Braf gene.

Mice

hCCR8(BALB/c)

Strain Name：BALB/cAnSmoc-Ccr8em1(hCCR8)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000048
Validation Data：Presence

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene.

Mice

hPD-1/hPD-L1/hOX40

Strain Name：C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00122
Validation Data：Absence

hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062) were crossed with hOX40(NM-HU-00041) to generate hPD-1/hPD-L1/hOX40.

Mice

hCD27(2)

Strain Name：C57BL/6Smoc-Cd27em3(hCD27)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190035
Validation Data：Presence

The endogenous mouse Cd27 gene was replaced by human CD27 gene. While hCD27 mice(Stock No.NM-HU-00093）have been pulled from shelves for some reasons.

Mice

Axl-KO

Strain Name：C57BL/6Smoc-Axlem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200044
Validation Data：Absence

Exon 3 of Axl gene was deleted to generate Axl knockout mice.

Mice

Pten-KO

Strain Name：C57BL/6Smoc-Ptenem3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18002
Validation Data：Absence

Exon5 of Pten gene was deleted to generate Pten knockout mice.

Mice

hCD24

Strain Name：C57BL/6Smoc-Cd24aem1(hCD24)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000060
Validation Data：Presence

The endogenous mouse Cd24a gene was replaced by human CD24 gene. While hCD24(2)(Stock No.NM-HU-215025) mice function similarly to hCD24 mice, for more detailed information please contact our technical advisor.

Mice

hBTLA(2)

Strain Name：C57BL/6Smoc-Btlaem2(hBTLA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190040
Validation Data：Presence

Extracellular domain of mouse Btla gene was replaced by human BTLA gene. While hBTLA mice(Stock No.NM-HU-18014）have been pulled from shelves for some reasons.

Mice

Fcgr1-KO

Strain Name：C57BL/6Smoc-Fcgr1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18033
Validation Data：Absence

The Fcgr1 knockout mouse model was obtained by knocking out all coding regions of mouse Fcgr1 gene.

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