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Models

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Mice

hC3

Strain Name:C57BL/6Smoc-C3em1(hC3)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000079
Validation Data:Presence

The endogenous mouse C3 gene was replaced by human C3 gene.

Mice

hHGF(NOD-scid)

Strain Name:NOD-PrkdcscidHgfem1(hHGF)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190062
Validation Data:Presence

The endogenous mouse Hgf gene was replaced by human HGF gene.

Mice

Zbtb46-2A-CreERT2

Strain Name:C57BL/6Smoc-Zbtb46em1(2A-CreERT2-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-18021
Validation Data:Presence

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Zbtb46 gene via homologous recombination to establish a tamoxifen inducible Zbtb46-CreERT2 tool stain. This strain can be used to knockout target gene in Zbtb46+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

Cd19-IRES-DTRGFP

Strain Name:C57BL/6Smoc-Cd19em2(IRES-DTREGFP)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190042
Validation Data:Presence

A IRES-DTREGFP expression cassette was knocked into the Cd19 gene stop codon site.

Mice

hGLP1R

Strain Name:C57BL/6Smoc-Glp1rem2(hGLP1R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200220
Validation Data:Presence

The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.

Mice

hCCR1

Strain Name:C57BL/6Smoc-Ccr1em3(hCCR1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190067
Validation Data:Absence

The endogenous mouse Ccr1 gene was replaced by human CCR1 gene.

Mice

Aqp5-Cre

Strain Name:C57BL/6Smoc-Aqp5em1(iCre-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200062
Validation Data:Presence

A iCre-WPRE-polyA expression cassette was knocked into the Aqp5 gene start codon site.

Mice

Aplnr-2A-DreERT2

Strain Name:C57BL/6Smoc-Aplnrem1(2A-DreERT2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00132
Validation Data:Absence

A 2A-DreERT2-SV40polyA coexpression cassette is inserted befor the stop codon of mouse Aplnr gene via homologous recombination to establish a tamoxifen inducible Aplnr-DreERT2 tool stain. This strain can be used to knockout target gene in Aplnr+ cells after tamoxifen treatment when crossed with mice which carry rox sites flanking target gene.

Mice

hTLR8

Strain Name:C57BL/6Smoc-Tlr8em2(TLR8)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190044
Validation Data:Presence

The endogenous mouse Tlr8 gene was replaced by human TLR8 gene.

Mice

Mefv-hMEFV*V726A

Strain Name:C57BL/6Smoc-Mefvem1(hMEFV-V726A)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200221
Validation Data:Absence

Exon 7-10 of the endogenous mouse Mefv gene was replaced by human mutation gene (exon7-10).

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