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Models

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Mice

hTLR2

Strain Name：C57BL/6JSmo-Tlr2tm2(hTLR2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190066
Validation Data：Presence

The endogenous mouse Tlr2 gene was replaced by human TLR2 gene.

Mice

R26-TetO-Dre-IRES-mtagBFP2

Strain Name：C57BL/6JSmo-Gt(ROSA)26Sorem1(SA-pA-Ins-Ins-TetO-Dre-IRES-BFP-pA-Ins-Ins)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190020

The SA-polyA-Ins-Ins-TetO-Dre-IRES-BFP-polyA-Ins-Ins cassette is inserted in mouse Rosa26 loci.

Mice

hIL7

Strain Name：C57BL/6JSmo-Il7tm1(hIL7)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190031
Validation Data：Presence

The endogenous mouse Il7 gene was replaced by human IL7 gene.

Mice

Ikzf3-KO

Strain Name：C57BL/6JSmo-Ikzf3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2104251

Exon 8 of Ikzf3 gene was deleted to generate Ikzf3 knockout mice.

Mice

Siglec1-Cre

Strain Name：C57BL/6JSmo-Siglec1em1(iCre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215032
Validation Data：Presence

iCre-polyA expression cassette was knocked into the Siglec1 gene.

Mice

hFCRN(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Fcgrttm2(FCGRT)Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-020
Validation Data：Presence

The background of this strain is NMG, and its endogenous Fcgrt gene is replaced with human FCGRT.

Mice

R26-CAG-LSL-dCas9-VPR-IRES-EGFP

Strain Name：C57BL/6JSmo-Gt(ROSA)26Sorem1(CAG-LSL-dCas9-VPR-IRES-EGFP-WPRE-pA)
Strain State：Repository Live | Cat. NO.：NM-KI-18004

These mice harbor a CAG-LSL-dCas9-VPR(VP64-p65-Rta)-eGFP-pA conditional expression cassette in mouse Rosa26 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

Mice

Bag3-Flox

Strain Name：C57BL/6JSmo-Bag3em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-2101856

These mice carry loxP sites flanking exon 4 of Bag3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Bag3 gene.

Mice

hCD3E/hCD28

Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E))Cd28tm2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210233

hCD3E(NM-HU-00114) was crossed with hCD28(NM-HU-190011) to generate hCD3E/hCD28 mice.

Mice

hCD3E/hCD38(2)

Strain Name：C57BL/6JSmo-Cd3etm1(hCD3E))Cd38tm2(hCD38)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210234

hCD3E(NM-HU-00114) was crossed with hCD38(2)(NM-HU-190059) to generate hCD3E/hCD38(2) mice.

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