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Models

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Mice

Il12a-Luc-2A-EGFP

Strain Name：C57BL/6JSmo-Il12aem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00024

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il12a.

Mice

hCD96

Strain Name：C57BL/6JSmo-Cd96tm2(hCD96)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000059
Validation Data：Presence

The endogenous mouse Cd96 gene was replaced by human CD96 gene.

Mice

hGCGR

Strain Name：C57BL/6JSmo-Gcgrtm(hGCGR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215004
Validation Data：Presence

The endogenous mice Gcgr gene was replaced by human GCGR gene.

Mice

hIL11/hIL11RA

Strain Name：C57BL/6JSmo-Il11tm1(hIL11)Il11ra1tm1(hIL11RA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210372
Validation Data：Presence

hIL11(NM-HU-204981) was crossed with hIL11RA (NM-HU-204982) to generate hIL11/hIL11RA mice.

Mice

Il1a-Luc-2A-EGFP

Strain Name：C57BL/6JSmo-Il1aem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00009
Validation Data：Presence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon.

Mice

hPD-L1/hVEGFR2

Strain Name：C57BL/6JSmo-Cd274tm1(hCD274)Kdrtm2(hKDR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000102

hPD-L1(NM-HU-00062) was crossed with hKDR(NM-HU-00098) to generate hPD-L1/hKDR.

Mice

Bmi1-IRES-CreERT2

Strain Name：C57BL/6JSmo-Bmi1em1(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200095
Validation Data：Presence

A IRES-CreERT2 expression cassette was knocked into the Bmi1 gene stop codon site.

Mice

hLAG3

Strain Name：B6.129S-Lag3tm1(hLAG3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00049
Validation Data：Presence

The endogenous mouse Lag3 gene exon1-7 was replaced by human LAG3 gene extracellular region by homologous recombination.

Mice

hIL1B

Strain Name：C57BL/6JSmo-Il1btm3(hIL1B)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190047
Validation Data：Presence

The endogenous mouse Il1b gene was replaced by human IL1B gene.

Mice

hPD-1/hPD-L1/hPD-L2

Strain Name：C57BL/6JSmo-Pdcd1lg2tm1(hPDCD1LG2)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190060

The endogenous mouse Pd-1/Pd-l1/Pdcd1lg2 gene was replaced by human PD-1/PD-L1/PDCD1LG2 gene.

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