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Mice

h4-1BB(2)/hCD3E(2)

Strain Name：C57BL/6JSmo-Tnfrsf9tm2(TNFRSF9)Cd3etm2(hCD3E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210409

h4-1BB(2)(NM-HU-190077) was crossed with hCD3E(2)(NM-HU-210023)to generate h4-1BB(2)/hCD3E(2) mice.

Mice

hCCR2

Strain Name：C57BL/6JSmo-Ccr2tm2(hCCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18026
Validation Data：Presence

The endogenous mouse Ccr2 gene was replaced by human CCR2 gene.

Mice

hB7H3

Strain Name：C57BL/6JSmo-Cd276tm2(hB7H3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00107
Validation Data：Presence

The endogenous mouse Cd276 gene was replaced by human CD276 gene.

Mice

h4-1BB(2)/hPD-1

Strain Name：C57BL/6JSmo-Tnfrsf9tm2(h4-1BB)Pdcd1tm1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200279

h4-1BB(2)(NM-HU-190077) was crossed with hPD-1(NM-HU-00015)to generate h4-1BB(2)/hPD-1 mice

Mice

Atp4b-IRES-CreERT2

Strain Name：C57BL/6JSmo-Atp4bem1(IRES-CreERT2-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210118
Validation Data：Presence

An IRES-CreERT2-WPRE-pA expression cassette was knocked into the Atp4b gene stop codon site. Besides, An IRES-CreERT2 expression cassette were knock into the Bhlha15 gene stop codon site to generate Atp4b-IRES-CreERT2(2)(Stock No. NM-KI-210119) mice.

Mice

hCTLA-4/Cd8a-IRES-Luc-2A-EGFP

Strain Name：C57BL/6JSmo-Ctla4tm1(hCTLA4)Cd8atm1(V5-IRES-luc-2A-EGFP)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210374

hCTLA4(NM-HU-00014) was crossed with Cd8a-IRES-Akaluc-2A-EGFP(NM-KI-18030) to generate hCTLA4/Cd8a-IRES-Akaluc-2A-EGFP mice.

Mice

H11-pT3(b)-hIL15-Flag

Strain Name：C57BL/6JSmo-Igs2tm(pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA-pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220128

pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA-pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA expression cassette was knocked into the the lgs2 (H11) locus.

Mice

Tmem119-2A-tdTomato-2A-DTR

Strain Name：C57BL/6JSmo-Tmem119em1(2A-tdTomato-2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210117
Validation Data：Presence

2A-tdTomato-2A-DTR expression cassette was knocked into the Tmem119 gene.

Mice

Adgre1-2A-CreERT2

Strain Name：C57BL/6JSmo-Adgre1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190025
Validation Data：Presence

A 2A-CreERT2 expression cassette was knocked into the Adgre1 gene stop codon site.

Mice

Ace2-2A-CreERT2

Strain Name：C57BL/6JSmo-Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200187
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.

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