Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Immunodeficient NMG Mice
Strain Name:C57BL/6JSmo-Il21rtm1(hIL21R)Il2rgtm1(IL2RG)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220004
hIL21R(NM-HU-210031) was crossed with hIL2RG(NM-HU-200007) to generate hIL21R/hIL2RG mice.
Strain Name:C57BL/6JSmo-Siglecfem1(kozak-DreER-WPRE-pA)Smoc Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200202
A kozak-DreER-WPRE-pA expression cassette was knocked into the Siglecf gene start codon site.
Strain Name:C57BL/6JSmo-Tpbgtm1(hTPBG)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200239 Validation Data:Presence
The endogenous mice Tpbg gene was replaced by human TPBG gene.
Strain Name:C57BL/6JSmo-Cd274tm1(hCD274)Siglec15tm1(hSIGLEC15)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000103
hPD-L1(NM-HU-00062) was crossed with hSIGLEC15(NM-HU-190037) to generate hPD-L1/hSIGLEC15.
Strain Name:C57BL/6JSmo-Uoxem1Smoc Strain State:Repository Live | Cat. NO.:NM-KO-191205 Validation Data:Presence | Publications:1piece
Uox-KO(2) mice(Stock No.NM-KO-191205)carry a knockout allele derived from the targeted deletion of exon 3-4.
Strain Name:C57BL/6JSmo-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd28tm2(hCD28)Cd38tm2(hCD38)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220115
hCD3EDG/hCD28(NM-HU-220113) mice were crossed with hCD3EDG/hCD38(NM-HU-220114) mice to generate hCD3EDG/hCD28/hCD38(2) mice.
Strain Name:C57BL/6JSmo-Cpa3em2(2A-CreERT2-WPRE-polyA)Smoc Strain State:Repository Live | Cat. NO.:NM-KI-200005 Validation Data:Presence
A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Cpa3 gene stop codon site.
Strain Name:C57BL/6JSmo-Mertkem1Smoc Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-200362
Exon 2 of Mertk gene was deleted to generate Mertk knockout mice.
Strain Name:C57BL/6JSmo-Pdcd1tm1(hPDCD1)Sema4dtm1(hSemA4D)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190033
hPD-1(NM-HU-00015) was crossed with hSEMA4D(NM-HU-00117) to generate hPD-1/hSEMA4D.
Strain Name:C57BL/6JSmo-Igfbp2tm1(hIGFBP2)Smoc Strain State:Repository Live | Cat. NO.:NM-HU-225085
The endogenous mouse Igfbp2 gene was replaced by human IGFBP2 gene.
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