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Models

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Mice

hTNFR2/hIL2RA

Strain Name：C57BL/6JSmo-Tnfrsf1btm2(hTNFRSF1B)Il2ratm1(hIL2RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210408

hTNFRSF1B(NM-HU-190010) was crossed with hIL2RA(NM-HU-190064) to generate hTNFRSF1B/hIL2RA mice.

Mice

hIl5

Strain Name：C57BL/6JSmo-Il5tm3(hIL5)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190001
Validation Data：Presence

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.

Mice

hDDR1

Strain Name：C57BL/6JSmo-Ddr1tm3(hDDR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225086
Validation Data：Presence

The endogenous mouse Ddr1 gene was replaced by human DDR1 gene.

Mice

Erbb2-Flox

Strain Name：C57BL/6JSmo-Erbb2em(flox)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-220557

These mice carry loxP sites flanking exon 2 of Erbb2 When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Erbb2 gene.

Mice

hCTLA-4/hCCR8(BALB/c)

Strain Name：BALB/cJSmo-Ccr8tm1(hCCR8)Ctla4tm1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220050

hCTLA4(BALB/c)(NM-HU-190078) was crossed with hCCR8(BALB/c)(NM-HU-2000048) to generate hCTLA4/hCCR8(BALB/c) mice．

Mice

hNECTIN4

Strain Name：C57BL/6JSmo-Nectin4tm1(hNECTIN4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210016
Validation Data：Presence

The endogenous mice Nectin4 gene was replaced by human NECTIN4 gene.

Mice

Avp-IRES-Cre

Strain Name：C57BL/6JSmo-Avpem1(IRES2-Cre-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200142
Validation Data：Presence

A IRES2-Cre-WPRE-polyA expression cassette was knocked into the Avp gene stop codon site. Avp encodes arginine vasopressin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying hypertension.

Mice

hIFNGR1/hIFNGR2

Strain Name：C57BL/6JSmo-Ifngr1tm3(hIFNGR1)Ifngr2tm(hIFNGR2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220003
Validation Data：Presence

hIFNGR1(NM-HU-190076) was crossed with hIFNGR2(NM-HU-215010) to generate hIFNGR1/hIFNGR2 mice.

Mice

hPD-1(BALB/c)

Strain Name：BALB/cJSmo-Pdcd1tm1(hPDCD1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190079
Validation Data：Presence

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

Mice

hFCRN(3)

Strain Name：C57BL/6JSmo-Fcgrttm3(hFCGRT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000032

The endogenous mouse Fcgrt gene was replaced by human FCGRT gene. While hFCRN(Stock No.NM-HU-00109）and hFCRN(2)(Stock No.NM-HU-190070) mice function similarly to hFCRN(3) mice,for more detailed information please contact our technical advisor.

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