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Models

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Mice

hPVR

Strain Name:C57BL/6JSmo-Pvrtm1(hPVR)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190012
Validation Data:Presence

The endogenous mouse Pvr gene was replaced by human PVR gene.

Mice

hCD2

Strain Name:C57BL/6JSmo-Cd2tm1(hCD2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-204986
Validation Data:Presence

The endogenous mice Cd2 gene was replaced by human CD2 gene.

Mice

hTIGIT(3)

Strain Name:C57BL/6JSmo-Tigittm3(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200244
Validation Data:Presence

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(Stock No.NM-HU-00053) mice function similarly to hTIGIT(3) mice ,for more detailed information please contact our technical advisor.

Mice

hCD3EDG

Strain Name:C57BL/6JSmo-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220120
Validation Data:Presence

The endogenous mouse Cd3e/Cd3d/Cd3g genes were replaced by human CD3E/CD3D/CD3G gene.

Mice

hFCGR2A

Strain Name:C57BL/6JSmo-Fcgr2btm3(hFCGR2A)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000071
Validation Data:Presence

The endogenous mouse Fcgr2b gene was replaced by human FCGR2A gene.

Mice

Drd1-2A-CreERT2

Strain Name:C57BL/6JSmo-Drd1em1(2A-CreERT2-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-18016
Validation Data:Presence

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Drd1 gene via homologous recombination to establish a tamoxifen inducible Drd1-CreERT2 tool stain. This strain can be used to knockout target gene in Drd1+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

hHLA-A11.1

Strain Name:C57BL/6JSmo-H2-K1tm1(hHLA-A*1101)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-204987
Validation Data:Presence

The endogenous mice H2-K1 gene was replaced by human HLA-A11.1 gene.

Mice

hIL10RA

Strain Name:C57BL/6JSmo-Il10ratm1(hIL10RA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-215072
Validation Data:Presence

The endogenous mouse Il10ra gene was replaced by human IL10RA gene.

Mice

hCD4

Strain Name:C57BL/6JSmo-Cd4tm1(hCD4) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00115
Validation Data:Presence

The endogenous mouse Cd4 gene was replaced by human CD4 gene .

Mice

hIFNGR2

Strain Name:C57BL/6JSmo-Ifngr2tm(hIFNGR2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-215010
Validation Data:Presence

The endogenous mouse Ifngr2 gene was replaced by human IFNGR2 gene.

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