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Models

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Mice

Atp4b-IRES-CreERT2(2)

Strain Name：C57BL/6Smoc-Atp4bem2(IRES-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210119

An IRES-CreERT2 expression cassette was knocked into the Atp4b gene stop codon site. Besides,An IRES-CreERT2-WPRE-pA expression cassette were knock into the Atp4b gene start codon site to generate Atp4b-IRES-CreERT2(Stock No. NM-KI-210118) mice. ATP4B could serve as a tumor suppressor in the tumorigenesis and progression. This strain is useful in studying the function of gastric parietal cells in gastric epithelial homeostasis. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cre-expressing cells after tamoxifen treatment.

Mice

Tnfrsf1a/Tnfrsf1b-KO

Strain Name：C57BL/6Smoc-Tnfrsf1aem1Smoc Tnfrsf1aem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18036

This strain is also called p55/p75-KO. The Tnfrsf1a and Tnfrsf1b double knockout mouse models were obtained by knocking out both exon 2-5 region of mouse Tnfrsf1a gene and exon2 of mouse Tnfrsf1b gene. Tnfrsf1a and Tnfrsf1b deletion (p55 and p75 deficiency) homozygous mice are viable and fertile, and these homozygous mice fail to bind TNF (tumor necrosis factor).

Mice

Apc-Flox

Strain Name：C57BL/6Smoc-Apctm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200013

These mice carry loxP sites flanking exon 15 of Apc gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Apc gene.

Mice

R26-LSL-Notch1C-IRES-nEGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-LSL-Notch1C-IRES-nEGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200036

These mice harbor a SA-LSL-Notch1C-IRES-nEGFP cassette in the Rosa26 locus generated by homologous recombination.Notch1C (mouse Notch1 ,amino acids 1749–2293)

Mice

pMMTV-Jag1-Tg(Balb/c)

Strain Name：BALB/cAnSmoc-Tg(pMMTV-Jag1)2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-TG-225004

These transgenic mice harbor pMMTV-Jag1 expression cassettes.

Mice

Trp53-LSL-R172H

Strain Name：C57BL/6Smoc-Trp53tm(LSL- R172H)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-220071

These mice carry a R172H conditional mutation of Trp53 gene.

Mice

R26-CAG-loxp-tdTomato-loxp2272-Tag-IRES-EGFP-2A-Luc-loxp-loxp2272

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-loxp-tdTomato-polyA-loxp2272-polyA-Wpre-Tag-IRES-EGFP-2A-Luciferase-loxp-loxp2272)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200033

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-loxp-tdTomato-polyA-loxp2272-polyA-Wpre-Tag-IRES-EGFP-2A-Luciferase-loxp-loxp2272 cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-CAG-LSL-Hgf-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-Hgf-IRES-Luciferase-2A-tdTomato-wpre-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200037

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-loxp-stop-loxp-Hgf-IRES-Luciferase-2A-tdTomato-wpre-polyA cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-CAG-LSL-Tgfa-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-Frt-2xpA-CAG-Frt-LSL-Tgfa-IRES-Luc-2A-EGFP-Wpre-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200038

These mice harbor a SA-Frt-2xpA-CAG-Frt-LSL-Tgfa-IRES-Luc-2A-EGFP-Wpre-pA cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-CAG-LSL-Vegfc-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-Frt-2xpA-CAG-Frt-LSL-Vegfc-IRES-Luc-2A-tdTomato-Wpre-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200039

These mice harbor a SA-Frt-2xpA-CAG-Frt-LSL-Vegfc-IRES-Luc-2A-tdTomato-Wpre-pA cassette in the Rosa26 locus generated by homologous recombination.

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