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Models

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Mice

Prg4-KO

Strain Name：C57BL/6Smoc-Prg4em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200428

Exon 3-8 of Prg4 gene was deleted to generate Prg4 knockout mice.

Mice

Apc-L850X

Strain Name：C57BL/6Smoc-Apcem1(L850X)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200001

Familial adenomatous polyposis (FAP) is a heritable condition in which affected individuals develop benign intestinal polyps. Often, polyps progress to colorectal carcinomas later in life. The mutation of C57BL/6-Apcem1(L850X)Smoc(NM-KI-200001) strain of SMOC refers to the ApcMin model (Jax: 002020 ), a useful model to study intestinal adenomas. The C57BL/6-Apcem1(L850X)Smoc strain is highly susceptible to spontaneous intestinal adenoma formation and can be used as a research model for human FAP. These mice carry a p.L850X mutation of Apc gene.

Mice

Stk11-Flox

Strain Name：C57BL/6Smoc-Stk11tm(flox)1Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-18014

These mice carry loxP sites flanking exon3-6 of the Stk11 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Stk11-Frox

Strain Name：C57BL/6Smoc-Stk11em1(frox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200251

These mice carry rox sites flanking exon3-6 of Stk11 gene. When crossed with a Dre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Stk11 gene.

Mice

Apoe-KO(2)

Strain Name：C57BL/6Smoc-Apoeem5Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190565

Apoe-KO(2) mice (Stock No.NM-KO-190565) carry a knockout allele derived from the targeted deletion of exon 2-4. While Apoe-KO mice (Stock No.NM-KO-00033) have been pulled from shelves for some reasons.

Mice

Il33-KO(2)

Strain Name：C57BL/6Smoc-Il33em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190436

Il33-KO(2) mice(Stock No.NM-KO-190436) carry a knockout allele derived from the targeted deletion of exon 3-7. While Il33-KO mice(Stock No.NM-KO-00099) have been pulled from shelves for some reasons and Il33-KO(3) mice(Stock No.NM-KO-210206) carrying the exon 2 deletion.

Mice

Ace2-KO

Strain Name：C57BL/6Smoc-Ace2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190906

exon 3-7 of Ace2 gene was deleted to generate Ace2 knockout mice.

Mice

Tfam-Flox

Strain Name：C57BL/6Smoc-Tfamtm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200173

These mice carry loxP sites flanking exon 10-13 of Tfam gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Tfam gene.

Mice

Usp1-Flox

Strain Name：C57BL/6Smoc-Usp1em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200052

These mice carry loxP sites flanking exon 3 of Usp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Usp1 gene.

Mice

Acly-Flox

Strain Name：C57BL/6Smoc-Aclyem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200076

These mice carry loxP sites flanking exon 9 of Acly gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Acly gene.

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