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Models

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Mice

Hif1a-Flox

Strain Name：C57BL/6Smoc-Hif1atm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-190065

These mice carry loxP sites flanking exon 2 of Hif1a gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Hif1a gene.

Mice

Cdkn2a-Flox(p16/p19-Flox)

Strain Name：C57BL/6Smoc-Cdkn2aem3(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200015

These mice carry loxP sites flanking exon 2 of the common region of Cdkn2a-p19ARF and Cdkn2a-p16INK4a transcripts.

Mice

Pdcd1-Flox

Strain Name：C57BL/6Smoc-Pdcd1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-210063

These mice carry loxP sites flanking exon 2-4 of Pdcd1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Pdcd1 gene.

Mice

Arg1-Flox

Strain Name：C57BL/6Smoc-Arg1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200062

These mice carry loxP sites flanking exon 5-8 of Arg1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Arg1 gene.

Mice

Chi3l1-Flox

Strain Name：C57BL/6Smoc-Chil1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-241991

These strains carry loxP sites flanking exon 3-5 of Chil1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Chil1 gene.

Mice

Eef2kmt-Flox

Strain Name：C57BL/6Smoc-Eef2kmtem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-234542

These strains carry loxP sites flanking exon 3-6 of Eef2kmt gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Eef2kmt gene.

Mice

Il1b-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1bem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00010

A Luciferase-2A-EGFP-pA cassette was inserted at ATG site of mouse Il1b gene. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1b.

Mice

Trdc-IRES-CreERT2

Strain Name：C57BL/6Smoc-Trdcem1(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-231464

The IRES-CreERT2 expression cassette was inserted after the termination codon of the mouse Trdc gene.

Mice

Hc-KO

Strain Name：C57BL/6Smoc-Hcem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190191

This Hc knockout mouse model was generated by knocking out the exon 6 region of the Hc.

Mice

Cdkn2a-Luc-2A-tdTomato-2A-CreERT2(p16-Luc-2A-tdTomato-2A-CreERT2)

Strain Name：C57BL/6Smoc-Cdkn2aem(Luc-tdTomato-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18039

A Luc-2A-tdTomato-2A-CreERT2-WPRE-pA cassette was fused in-frame with exon2 of p16INK4a transcript such that the exogenous proteins would be translated followed by the first 62aa of Cdkn2a.

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