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Models

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Mice

Rag2/IL2rg-KO(BALB/c)

Strain Name：BALB/cAnSmoc-Rag2em1IL2rgem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-210231

Exon 3 of Rag2 and exon 2 of IL2rg gene was deleted to generate Rag2 and IL2rg knockout mice.

Mice

Bmal1-KO

Strain Name：C57BL/6Smoc-Bmal1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-205015

Exon 8 of Bmal1 gene was deleted to generate Bmal1 knockout mice.

Mice

Chil1-KO

Strain Name：C57BL/6Smoc-Chil1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190777

Exon 3 of Chil1 gene was deleted to generate Chil1 knockout mice.

Mice

Pdk3-KO

Strain Name：C57BL/6Smoc-Pdk3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200878

Exon 2 of Pdk3 gene was deleted to generate Pdk3 knockout mice.

Mice

Pcsk9-KO

Strain Name：C57BL/6Smoc-Pcsk9em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200784

Exon 2-5 of Pcsk9 gene was deleted to generate Pcsk9 knockout mice.

Mice

Tmem164-KO

Strain Name：C57BL/6Smoc-Tmem164em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-234906

The exon 4 of Tmem164 gene was deleted to generate Tmem164 knockout mouse.

Mice

MHCII/B2m-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1B2m em1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-014

All sequences from the upstream of  mouse H2-Ab1 gene exon 2  to the upstream of the H2-Ea-ps gene  exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models.Also, B2m gene was knocked out. These MHC class I and II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins and B2m of class I.

Mice

Col4a5-R471X

Strain Name：C57BL/6Smoc-Col4a5em1(R471X)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200183

These mice carry a R471X mutation of Col4a5 gene.

Mice

hMAPT-P301S

Strain Name：C57BL/6Smoc-Maptem1hMAPT-P301SSmoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-233262

These strains carry a P301S mutation of hMAPT gene.

Mice

Bmal1-Flox

Strain Name：C57BL/6Smoc-Bmal1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200063

These mice carry loxP sites flanking exon 8 of Bmal1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Bmal1 gene.

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