Welcome to Advanced Search

Models

About 40,023 results
Mice

H2/H2-K1-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1h2em2H2-K1em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-NSG-006

Exon 2 of H2;H2-K1 gene was deleted to generate H2;H2-K1 knockout mice.

Mice

R26-pVillin1-hCYP3A4-IRES-tdTomato(FVB)

Strain Name：FVB-Gt(ROSA)26Sorem1(Gut-CYP3A4-IRES-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18033

Intestinal expression of the CYP3A enzyme in the human body can cause significant intestinal metabolism of the compound, resulting in impaired drug absorption. This knock-in model was generated by inserting the human CYP3A4 cDNA driven by the Villin1 promoter together with the IRES-tdTomato reporter gene into mosue Rosa26 site, which can be crossed with the Cyp3a13 gene knockout and other Cyp3a family genes knockout mice to obtain intestinal-expressed CYP3A4 humanized mouse model in order to determine the contribution of intestinal metabolism to the absorption and distribution of test article.

Mice

Arhgef10-KO

Strain Name：C57BL/6Smoc-Arhgef10em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 5 of Arhgef10 gene was deleted to generate Arhgef10 knockout mice.

Mice

Xirp1-KO

Strain Name：C57BL/6Smoc-Xirp1em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 2 of Xirp1 gene was deleted to generate Xirp1 knockout mice.

Mice

A4galt-KO

Strain Name：C57BL/6Smoc-A4galtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200001

Exon 3 of A4galt gene was deleted to generate A4galt knockout mice.

Mice

C1qa-KO

Strain Name：C57BL/6Smoc-C1qaemSmoc
Strain State：Repository Live | Cat. NO.：NM-KO-210110

exon 3 of C1qa gene was deleted to generate C1qa knockout mice.

Mice

Apoa2-KO

Strain Name：C57BL/6Smoc-Apoa2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200035

Exon 3 of Apoa2 gene was deleted to generate Apoa2 knockout mice.

Mice

Lepr-KO

Strain Name：C57BL/6Smoc-Leprem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190663

Exon 5 of Lepr gene was deleted to generate Lepr knockout mice.

Mice

Ikzf3-KO

Strain Name：C57BL/6Smoc-Ikzf3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2104251

Exon 8 of Ikzf3 gene was deleted to generate Ikzf3 knockout mice.

Mice

hCTLA-4(2)

Strain Name：C57BL/6Smoc-Ctla4em2(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190038

Extracellular domain of mouse Ctla4 gene was replaced by human CTLA4 gene. While hCTLA4(Stock No.NM-HU-00014) mice function similarly to hCTLA4(2) mice,for more detailed information please contact our technical advisor.

Email Back to top