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Models

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Mice

HLA-A24.2/B2M

Strain Name：C57BL/6Smoc-H2-D1em1(hB2M-linker-HLA-A24.2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-241051

The endogenous mouse H2-D1 gene was replaced by human B2M gene.

Mice

R26-CAG-LSL-Coro1a

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Coro1a-linker-3xFlag-HA-WPRE-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-215009

A CAG-LSL-Coro1a-linker-3xFlag-HA-WPRE-pA expression cassette was knocked into the Rosa26 locus.

Mice

HLA-A11.1/B2M(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1B2mem1(hB2M-linker-HLA-A*1101/H2-D1)Smoc
Strain State：Developing | Cat. NO.：NM-HU-252346

The endogenous mouse B2m gene was replaced by hB2M-linker-HLA-A*1101/H2-D1 gene.

Mice

HLA-A2.1/B2M(NMG)(2)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1B2mem1(hB2M-linker-HLA-A*0201/H2-D1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-241683

The endogenous mouse B2m gene was replaced by hB2M/HLA-A2.1/H2-D1 gene.

Mice

HLA-A24.2/B2M(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1B2mem1(hB2M-linker-HLA-A*2402/H2-D1)Smoc
Strain State：Developing | Cat. NO.：NM-HU-252347

The endogenous mouse B2m gene was replaced by hB2M-linker-HLA-A*2402/H2-D1 gene.

Mice

HLA-A3.1/B2M(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1B2mem1(hB2M-linker-HLA-A*0301/H2-D1)Smoc
Strain State：Developing | Cat. NO.：NM-HU-252345

The endogenous mouse B2m gene was replaced by hB2M-linker-HLA-A*0301/H2-D1 gene.

Mice

hIDO1/HLA-A2.1/B2M

Strain Name：C57BL/6Smoc-B6;129S-Ido1tm1(hIDO1)SmocB2mem1(hB2M-linker-HLA-A*0201/H2-D1)
Strain State：Repository Live | Cat. NO.：NM-XA-252091

The hIDO1 (NM-HU-00061) was crossed with HLA-A2.1/B2M(NM-HU-241353) to generate hIDO1/HLA-A2.1/B2M mice.

Mice

hPD-1/hPD-L1/HLA-A2.1/B2M

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)SmocB2mem1(hB2M-linker-HLA-A*0201/H2-D1)
Strain State：Repository Live | Cat. NO.：NM-XA-252092

The hPD-1/hPD-L1 (NM-HU-00100) was crossed with HLA-A2.1/B2M(NM-HU-241353) to generate hPD-1/hPD-L1/HLA-A2.1/B2M mice.

Mice

C57BL/6

Strain Name：C57BL/6Smoc
Strain State：Repository Live | Cat. NO.：SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Mice

mB2m-hFCRN(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Fcgrtem1(B2m-FCGRT)Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-018

A B2m-Linker-FCGRT-WPRE-polyA expression cassette was knocked into the Fcgrt gene exon3 of the NMG(NM-NSG-001) mice.

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