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Mice

Bhlha15-CreERT2

Strain Name：C57BL/6Smoc-Bhlha15em1(CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200080
Validation Data：Presence

The coding region of Bhlha15 gene was replaced by a CreERT2 expression cassette.Besides,a kozak-CreERT2-WPRE-polyA expression cassette were knock into the Bhlha15 gene start codon site to generate Bhlha15-CreERT2(2)(Stock No. NM-KI-200158) mice. Bhlha15(basic helix-loop-helix family member a15) is also known as Mist1. The gene product is involved in controlling exocrine secretion from the pancreas, small intestine and stomach. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Bhlha15.

Mice

hIL7R

Strain Name：C57BL/6Smoc-Il7rtm1(hIL7R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210027
Validation Data：Presence

The endogenous mice Il7r gene was completely or partially replaced by human IL7R gene via ESC targeting.

Mice

Foxl1-2A-CreERT2

Strain Name：C57BL/6Smoc-Foxl1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00135
Validation Data：Presence

A 2A-CreERT2 coexpression cassette is inserted before the stop codon of mouse Foxl1 gene via homologous recombination to establish a Foxl1-CreERT2 recombinase tool stain. This strain can be used to knockout target gene inFoxl1+ cells after tamoxifen treatment when crossed with flox mice.

Mice

Alb-IRES-Cre

Strain Name：C57BL/6Smoc-Albem1(IRES-iCre-WPRE-pA)Smoc
Strain State：Developing | Cat. NO.：NM-KI-200075

A IRES-iCre-WPRE-pA expression cassette was knocked into the Alb gene stop codon site.

Mice

Il18-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il18em1(Luc-eGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00032
Validation Data：Presence

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il18.

Mice

hMAPT

Strain Name：C57BL/6Smoc-Mapttm1(hMAPT)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200116
Validation Data：Presence

The endogenous mouse Mapt gene was replaced by human MAPT gene.

Mice

hIL4-Tg(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Tg(hIL4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-215004
Validation Data：Presence

These transgenic mice carry humanized IL4.

Mice

Slc17a6-IRES-Cre

Strain Name：C57BL/6Smoc-Slc17a6em1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200087
Validation Data：Presence  |  Publications：1piece

A IRES-iCre expression cassette was knocked into the Slc17a6 gene stop codon site.

Mice

Cd2-2A-CreERT2

Strain Name：C57BL/6Smoc-Cd2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18017
Validation Data：Presence

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Cd2 gene via homologous recombination to establish a tamoxifen inducible Cd2-CreERT2 tool stain. This strain can be used to knockout target gene in T cells and B cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

Map2-2A-CreERT2

Strain Name：C57BL/6Smoc-Map2em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00037
Validation Data：Presence  |  Publications：1piece

Map2 is a marker of mature neurons. A 2A-CreERT2 cassette was inserted before the translational termination site of the Map2 locus.

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