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Mice

Hopx-2A-DreERT2

Strain Name:C57BL/6Smoc-Hopxem1(2A-DreERT2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190035
Validation Data:Presence  |  Publications:1piece

A 2A-DreERT2 expression cassette was knocked into the Hopx gene stop codon site.

Mice

R26-CAG-LSL-dCas9-VPR-IRES-EGFP

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-dCas9-VPR-IRES-EGFP-WPRE-pA)
Strain State:Repository Live | Cat. NO.:NM-KI-18004

These mice harbor a CAG-LSL-dCas9-VPR(VP64-p65-Rta)-eGFP-pA conditional expression cassette in mouse Rosa26 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

Mice

hIL4/hIL4R

Strain Name:C57BL/6Smoc-Il4tm3(hIL4)Il4ratm1(hIL4R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000106
Validation Data:Presence

These mice are obtained through breeding of two single gene humanized mice.

Mice

Emx1-IRES-Cre

Strain Name:C57BL/6Smoc-emx1em1(IRES-Cre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200149
Validation Data:Presence

A IRES-Cre expression cassette was knocked into the Emx1 gene stop codon site.

Mice

Ctsk-2A-Cre

Strain Name:C57BL/6Smoc-Ctskem1(2A-Cre-Wpre-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190019
Validation Data:Presence  |  Publications:1piece

The 2A-Cre-Wpre-polyA cassette is inserted before 3'UTR region of Ctsk gene.

Mice

R26-CAG-LSL-hTM6SF2*E167K-EGFP

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-Frt-2xpolyA-CAG-Frt-LSL-TM6SF2-IRES-GFP-WPRE-PA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200017

These mice harbor a SA-Frt-2xpolyA-CAG-Frt-LSL-TM6SF2-IRES-GFP-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

Mice

Ctsk-2A-CreERT2

Strain Name:C57BL/6Smoc-Ctskem1(2A-CreERT2-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200067
Publications:1piece

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ctsk gene stop codon site.

Mice

hPD-L1/hVISTA

Strain Name:C57BL/6Smoc-Visrtm1(hVSIR)Cd274tm1(hCD274)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000094

hPD-L1(NM-HU-00062) was crossed with hVISTA(NM-HU-00118) to generate hPD-L1/hVISTA.

Mice

hIL21R

Strain Name:C57BL/6Smoc-Il21rtm1(hIL21R)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210031
Validation Data:Presence

The endogenous mice Il21r gene was completely or partially replaced by human IL21R gene via ESC targeting.

Mice

Col2a1-2A-CreERT2

Strain Name:C57BL/6Smoc-Col2a1em1(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18029
Validation Data:Presence  |  Publications:1piece

A 2A-CreERT2 expression cassette was knocked into the stop codon of Col2a1 gene to establish a Col2a1-CreERT2 recombinase tool mouse.The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

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