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Mice

Cd2-2A-CreERT2

Strain Name:C57BL/6Smoc-Cd2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18017

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Cd2 gene via homologous recombination to establish a tamoxifen inducible Cd2-CreERT2 tool stain. This strain can be used to knockout target gene in T cells and B cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

Ctsk-2A-Cre

Strain Name:C57BL/6Smoc-Ctskem1(2A-Cre-Wpre-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190019

The 2A-Cre-Wpre-polyA cassette is inserted before 3'UTR region of Ctsk gene.

Mice

Calb2-IRES-Cre

Strain Name:C57BL/6Smoc-Calb2em1(IRES-iCre-SV40-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200102

A IRES-iCre expression cassette was knocked into the Calb2 gene stop codon site. Calb2 gene encodes calbindin 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. The protein plays a key role in the nervous system.

Mice

Alb-IRES-Cre

Strain Name:C57BL/6Smoc-Albem1(IRES-iCre-WPRE-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-200075

A IRES-iCre-WPRE-pA expression cassette was knocked into the Alb gene stop codon site.

Mice

H11-pAlb-hALB-IRES-Luc

Strain Name:C57BL/6Smoc-Igs2em1(ALB promoter-human ALB-IRES-Luciferase-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200322

An ALB promoter-human ALB-IRES-Luciferase-polyA expression cassette was knocked into the H11 locus.

Mice

Axin2-CreERT2

Strain Name:C57BL/6Smoc-Axin2em1(CreERT2-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200109

A CreERT2-pA expression cassette was knocked into the Axin2 gene start codon site. As Axin2 is an intracellular protein, it is essential for identifying a surface marker for stem cell purification. When these Axin2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Axin2 expressing cells.

Mice

Dppa3-IRES-Cre

Strain Name:C57BL/6Smoc-Dppa3em1(IRES-Cre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00040

The IRES-Cre cassette was inserted into 3'UTR of Dppa(Stella) gene which express during embryonic development.

Mice

Col2a1-2A-CreERT2

Strain Name:C57BL/6Smoc-Col2a1em1(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18029

A 2A-CreERT2 expression cassette was knocked into the stop codon of Col2a1 gene to establish a Col2a1-CreERT2 recombinase tool mouse.The strain cannot breed homozygotes, and it is recommended to use heterozygotes for research.

Mice

Isl1-CreERT2

Strain Name:C57BL/6Smoc-Isl1em1(CreERT2) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00013

CreERT2 was inserted at the start codon (ATG site). The KI mice have a tamoxifen-inducible cre-mediated recombination system.

Mice

Drd1-2A-CreERT2

Strain Name:C57BL/6Smoc-Drd1em1(2A-CreERT2-WPRE-pA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-18016

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Drd1 gene via homologous recombination to establish a tamoxifen inducible Drd1-CreERT2 tool stain. This strain can be used to knockout target gene in Drd1+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

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