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Mice

R26-SA-LNL-C1qtnf1

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-LNL-C1qtnf1-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190129

These mice harbor a SA-Loxp-Neo-polyA-Loxp-C1qtnf1-polyA cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-CAG-LSL-SoNar

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-SoNar-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215000

A CAG-LSL-SoNar-WPRE-polyA expression cassette was knocked into the Rosa26 locus.

Mice

Rag2-KO(Rag2-EGFP)

Strain Name：B6;129S-Rag2tm1(loxP-EGFP-PolyA-loxP-Neo-loxP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00070

A loxP-EGFP-PolyA-loxP-Neo-loxP expression cassette was knocked into the Rag2 gene start codon site. As a Rag2 knockout mouse model, this stain can be used in subcutaneous inoculation of liver cancer tissues and tumor cells. Tumors can esaily form and grow. The amount of T and B lymphocytes in peripheral blood of mice was extremely low tested by FACS, which was comparable to or lower than that of Nude mice, and there was a significant difference compared with wild type mice. The pathological sections of HE staining of tumor tissues showed that the tumor sections of Rag2 KO mice and Nude mice were similar. This strain has the potential to replace Nude, NOD-SCID mice as a tumor-bearing mouse model.

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

R26-CAG-LSL-SLIT3*R1479C

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-SLIT3-R1479C-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225092

CAG-LSL-SLIT3*R1479C-WPRE-pA expression cassette was knocked into the Rosa26 locus.

Mice

R26-CAG-LSL-Wtap-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Wtap-3xFLAG-IRES-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190058

These mice harbor a CAG-LSL-Wtap-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.

Mice

R26-CAG-LSL-Virma-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Virma-3xFLAG-IRES-EGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190057

These mice harbor a CAG-LSL-Virma-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.

Mice

Olig2-IRES-Cre

Strain Name：C57BL/6Smoc-Olig2em1(IRES-iCre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200114

A IRES-iCre expression cassette was knocked into the Olig2 gene stop codon site via CRISPR/Cas9 mediated recombination.

Mice

Wnt5b-IRES-CreERT2-2A-tdTomato

Strain Name：C57BL/6Smoc-Wnt5bem(IRES-CreERT2-P2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215083

IRES-CreERT2-P2A-tdTomato expression cassette was knocked into the Wnt5b gene .

Mice

R26-CAG-LSL-Ythdc2-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Ythdc2-3xFLAG-IRES-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190060

These mice harbor a CAG-LSL-Ythdc2-3xFLAG-IRES-EGFP cassette in the Rosa26 locus generated by homologous recombination.

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