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Models

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Mice

R26-CAG-LSL-Luc-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-luci-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18051

A CAG-loxP STOP-loxP-luci-2A-tdTomato-WPRE-polyA cassette was knocked into the mouse ROSA26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that luciferase and tdTomato fluorescent protein could be expressed for cell tracing.

Mice

Alb-2A-DTRGFP(NMG)

Strain Name：NOD-Prkdcscid Il2rgem1Albem1(2A-DTRGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215047

2A-DTRGFP expression cassette was knocked into the Alb gene.

Mice

hTLR8/Lyz2-DTREGFP

Strain Name：C57BL/6Smoc-Lyz2em3(IRES-DTREGFP)Tlr8tm2(TLR8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200259

NM-KI-190041 was crossed with NM-HU-190044 to generate hTLR8/Lyz2-IRES-DTREGFP mice.

Mice

R26-CAG-LSL-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-R-tdTomato-2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210094

These mice harbor a CAG-LSL-R-tdTomato-2A-DTR cassette in the Rosa26 locus generated by homologous recombination.

Mice

Acta2-CreERT2

Strain Name：C57BL/6Smoc-Acta2em1(CreERT2-Wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200074

A CreERT2-Wpre-polyA expression cassette was knocked into the Acta2 gene start codon site.

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

hANGPTL3(4)

Strain Name：C57BL/6Smoc-Angptl3em1(hANGPTL3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210036

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(3)(Stock No.NM-HU-210037) mice function similarly to hANGPTL3(2) mice, for more detailed information please contact our technical advisor.

Mice

Adgre1-2A-CreERT2

Strain Name：C57BL/6Smoc-Adgre1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190025

A 2A-CreERT2 expression cassette was knocked into the Adgre1 gene stop codon site.

Mice

Foxp3-IRES-DTR-2A-tdTomato(BALB/c)

Strain Name：BALB/cAnSmoc-Foxp3em9(IRES-DTR-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200213

A IRES-DTR-2A-tdTomato expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

Ly6g-Cre-2A-tdTomato

Strain Name：C57BL/6Smoc-Ly6gem2(iCre-P2A-tdTomato-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200219

A iCre-P2A-tdTomato-polyA expression cassette was knocked into the Ly6g gene start codon site.

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