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Mice

Ace2-2A-CreERT2

Strain Name：C57BL/6Smoc-Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200187
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.

Mice

Alb-2A-DTRGFP(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Albem1(2A-DTRGFP)Smoc
Strain State：Developing | Cat. NO.：NM-KI-215047

2A-DTRGFP expression cassette was knocked into the Alb gene.

Mice

Cdkn2a-Luc-2A-tdTomato-2A-CreERT2(p16-Luc-2A-tdTomato-2A-CreERT2)

Strain Name：C57BL/6Smoc-Cdkn2aem(Luc-tdTomato-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18039
Validation Data：Presence  |  Publications：1piece

A Luc-2A-tdTomato-2A-CreERT2-WPRE-pA cassette was fused in-frame with exon2 of p16INK4a transcript such that the exogenous proteins would be translated followed by the first 62aa of Cdkn2a.

Mice

hANGPTL3(4)

Strain Name：C57BL/6Smoc-Angptl3tm1(hANGPTL3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210036
Validation Data：Presence

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(3)(Stock No.NM-HU-210037) mice function similarly to hANGPTL3(2) mice, for more detailed information please contact our technical advisor.

Mice

Foxp3-IRES-DTR-2A-tdTomato(BALB/c)

Strain Name：BALB/cAnSmoc-Foxp3em9(IRES-DTR-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200213
Validation Data：Presence

A IRES-DTR-2A-tdTomato expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

Aicda-Cre

Strain Name：C57BL/6Smoc-Aicdaem1(Cre-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200160
Validation Data：Presence

A Cre-WPRE-polyA expression cassette was knocked into the Aicda gene start codon site.

Mice

Atp4b-IRES-CreERT2

Strain Name：C57BL/6Smoc-Atp4bem1(IRES-CreERT2-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210118
Validation Data：Presence

An IRES-CreERT2-WPRE-pA expression cassette was knocked into the Atp4b gene stop codon site. Besides, An IRES-CreERT2 expression cassette were knock into the Bhlha15 gene stop codon site to generate Atp4b-IRES-CreERT2(2)(Stock No. NM-KI-210119) mice.

Mice

R26-CAG-LSL-Luc-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-luci-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18051
Validation Data：Presence

A CAG-loxP STOP-loxP-luci-2A-tdTomato-WPRE-polyA cassette was knocked into the mouse ROSA26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that luciferase and tdTomato fluorescent protein could be expressed for cell tracing.

Mice

Ly6g-Cre-2A-tdTomato

Strain Name：C57BL/6Smoc-Ly6gem2(iCre-P2A-tdTomato-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200219
Validation Data：Presence

A iCre-P2A-tdTomato-polyA expression cassette was knocked into the Ly6g gene start codon site.

Mice

hTLR8/Lyz2-DTREGFP

Strain Name：C57BL/6Smoc-Lyz2tm3(IRES-DTREGFP)Tlr8tm2(TLR8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200259

NM-KI-190041 was crossed with NM-HU-190044 to generate hTLR8/Lyz2-IRES-DTREGFP mice.

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