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Models

About 38 results
Mice

Wnt1-Dre

Strain Name：C57BL/6Smoc-Wnt1em1(Dre-Wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200176

A Dre-Wpre-polyA expression cassette was knocked into the Wnt1 gene start codon site. Wnt1 gene is involved in stem cell poliferation in multiple systems, including the hematopoietic system and the embryonic nervous system. This strain may be useful for studying central nervous system development. When crossed with a strain carrying a gene flanked by rox sites, the flanked gene will be removed in cells expressing dre.

Mice

Jag1-Flox

Strain Name：C57BL/6Smoc-Jag1em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200112

These mice carry loxP sites flanking exon 4 of Jag1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Jag1 gene.

Mice

Amotl2-KO

Strain Name：C57BL/6Smoc-Amotl2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190914

Exon 3 of Amotl2 gene was deleted to generate Amotl2 knockout mice.

Mice

Zfp42-Flox

Strain Name：B6;129S-Zfp42tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00057

These mice carry loxP sites on either side of exon 5. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Etv1-CreERT2

Strain Name：C57BL/6Smoc-Etv1em1(CreERT2-SV40-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200105

A CreERT2 expression cassette was knocked into the Etv1 gene start codon site. ETV1 expression is enriched in fast conduction tissues of embryonic and adult mammalian hearts. And ETV1 expression is upregulated in the atrial tissue of patients with permanent atrial fibrillation. Etv-CreERT2 mice can be applied to heart disease research. ETV1 is also expressed in retinal ganglion cells of adult mice, and the mouse model can be used to study how retinal ganglion cells contribute to visual processing in the brain.

Mice

Dppa3-IRES-Cre

Strain Name：C57BL/6Smoc-Dppa3em1(IRES-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00040

The IRES-Cre cassette was inserted into 3'UTR of Dppa(Stella) gene which express during embryonic development.

Mice

Snx3-KO

Strain Name：C57BL/6Smoc-Snx3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201912

Snx3-KO mice (Stock No.NM-KO-201912) carry a knockout allele derived from the targeted deletion of exon 2-3. While Snx3-KO(2) mice(Stock No.NM-KO-210172）carrying the exon 3 deletion. It has been reported in the literature that homozygous for this gene knockout will die in the embryonic stage.

Mice

Snx3-KO(2)

Strain Name：C57BL/6Smoc-Snx3emSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210172

Snx3-KO(2) mice(Stock No.NM-KO-210172） carry a knockout allele derived from the targeted deletion of exon 3. While Snx3-KO mice(Stock No.NM-KO-201912）carrying the exon 2-3 deletion. It has been reported in the literature that homozygous for this gene knockout will die in the embryonic stage.

Mice

Palld-KO

Strain Name：B6;129S-Palldtm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00009

Palld gene knockout strain.

Mice

Nodal-KO

Strain Name：C57BL/6Smoc-Nodalem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190536

Exon 2-3 of Nodal gene was deleted to generate Nodal knockout mice.

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