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Customization

Using SMOC’s gene targeting artificial intelligent expert system-Smarteddi, you can input the name of the gene you want to knockout and the cloud-based search engine will show you the solution. 

Animal Welfare

laboratory animal welfare

Shanghai Model Organisms Center (SMOC) has always placed significant emphasis on the welfare of laboratory animals and treats all laboratory animals with respect.

Fibrosis

liver fibrosis model

The mouse liver fibrosis model can be generated by surgery or drug induction, which can be used to study the role of genes and proteins in the development of liver fibrosis, to explore the mechanisms underlying liver fibrosis, and to carry out drug efficacy evaluations.

Smad4 CKO Mouse Model

Our own-developed Smad4 conditional knockout mice (Smad4-CKO) can be used to study cell proliferation and tumor suppression.

Zebrafish · Nematode

Provide services base on zebrafish and nematode research technology platform.

Resources & Support

resource center support center

Obtain our product brochures, view our past publications, download animal health reports, browse products and literature, explore a variety of common issues, and get online support from our technical experts.

Popular Model Organisms

genetically modified organisms transgenic organisms genetically modified organisms examples

Model organisms are instrumental to the study of gene functions. Gene editing technology has always played a crucial role in the research on gene functions, diseases and drug discovery, through its application in genetic engineering of model organisms, mimicking of human diseases, as well as observation of physiological or pathological changes. In particular, the CRISPR/Cas9 technology has achieved remarkable breakthroughs in recent years, significantly improving the efficiency of genetic engineering in model organisms, and facilitating more extensive and in-depth applications of animal models in various research fields.

Gene tracking

marker gene gene tracking

Gene tracers are an important application for genetically engineered mice. Through gene knock-in, exogenous tracer genes were knocked into endogenous genes, enabling labeling and tracing of genes.

Blood Analysis

Mouse serum mouse serum albumin

At Shanghai Model Organisms Center, we use an automatic biochemical analyzer to measure a specific chemical composition of serum according to the principle of photoelectric colorimetry. This can be used to assess liver and kidney functions or measure blood sugar, blood lipids, and electrolytes.

Services

genetic engineering genetic animals genetic engineering examples

Shanghai Model Organisms offers a full range of model organism services, including model customization services, research-ready models, breeding, phenotyping and drug screening. Mouse, rat, zebrafish and C. elegans models are available to meet different research needs.