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Fluorescent tracking

fluorescent label fluorescent tag fluorescent genes

Exogenous fluorescent genes were knocked in to endogenous genes and fluorescence expression was used to reflect the expression status of genes.

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Cancer Model

research on cancer cancer model mouse models of cancer

The laboratory mouse is widely considered as a valid and affordable model organism for studying human disease. Mouse models of cancer not only enable researchers to understand the genetic basis of tumor development in complicated and dynamic physiological systems, but also serve as irreplaceable tools for developing and testing new therapies.  Shanghai Model Organisms Center offers a variety of mouse models of cancer to meet the needs of both academic and industry partners.

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Database

mouse genome database

Here you can find links to databases for mouse genomes and other resources.

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Gene overexpression

gene overexpression gene overexpression protocol gene overexpression techniques

Generate a mouse model in which an exogenous gene is introduced and overexpressed. An overexpression model can be used to investigate gene functions, promoter functions, or model the pathogenesis of human disease. Depending on the method to introduce foreign DNA, a random transgenes or targeted conditional overexpression model can be created.

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Rb1 CKO Mouse Model

With the ability to avoid the risk of death caused by homozygous and systemic knockout, our own-developed Rb1 conditional knockout mice (Rb1-CKO) can be used to study cancer, cell cycle or aging.

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Applications of Animal Models

cell model animal model organism animal model

The model animal has played an important role in the history of life sciences and medicine, with a wide range of application in biology, medicine, molecular biology, molecular genetics, immunology and other fields.

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Mouse models for cancer research

Tumor bearing Mouse DEN model PDX model CDX model

Shanghai Model Organisms Center provides multiple types of tumor-bearing mouse models for cancer research and drug efficacy testing, including cell line-derived xenograft model (CDX) and patient-derived xenograft model (PDX). While PDX models better reflect the heterogeneity and diversity of human cancers, CDX models allow researchers to advance their pre-clinical drug development in a cost- and time-efficient manner.

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Drug Screening

drug screening high throughput screening for drug discovery

With a comprehensive model organisms service platform that generates the mouse, zebrafish and C. elegans models, Shanghai Model Organisms enables high-throughput drug screening as well as the evaluation and research on drug efficacy, thus accelerating drug development and achieving greater accuracy in the prediction of in vivo interactions.

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Contact Us

As a biotechnology company specializing in animal model R&D, rearing and breeding, as well as analysis and testing, GenoBioTX is dedicated to providing our clients with comprehensive, convenient and professional animal model services.

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