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Models

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Mice

hIL5/hIL5R(3)

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Il5raem3(hIL5RA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220011

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.

Mice

hCTLA-4/hCD28(BALB/c)

Strain Name：BALB/cAnSmoc-Ctla4em1(hCTLA4)Cd28em1(hCD28)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-200226

The endogenous mice Ctla4 and Cd28 gene was replaced by human CTLA4 and CD28 gene.

Mice

Il6st-Y757F/V760A

Strain Name：C57BL/6Smoc-Il6stem(Y757F-V760A)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-220045

These mice carry Y757F and V760A mutations of Il6st gene.

Mice

Paqr4-KO

Strain Name：B6;129S-Paqr4tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00044

Neo cassette replaces exon2 and exon 3.

Mice

Cyp3a-KO(FVB)

Strain Name：FVB-Cyp3a57em1Cyp3a59em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18056

All genes between Cyp3a57 and Cyp3a59 (including Cyp3a11, Cyp3a16, Cyp3a25, Cyp3a41, Cyp3a44, Cyp3a57, Cyp3a58-ps, Cyp3a59) were knocked out to generate Cyp3a-KO(FVB) mice (Stock No.NM-KO-18056). All genes between Cyp3a57 and Cyp3a59 (including Cyp3a11, Cyp3a16, Cyp3a25, Cyp3a41, Cyp3a44, Cyp3a57, Cyp3a58-ps, Cyp3a59) and Cyp3a13 were knocked out to generate Cyp3a-KO(FVB,2) mice (Stock No.NM-KO-190427).

Mice

hCD59

Strain Name：C57BL/6Smoc-Cd59a,Cd59btm1(hCD59)Smoc
Strain State：Developing | Cat. NO.：NM-HU-234072

The endogenous mouse Cd59a and Cd59b genes were replaced by human CD59 gene.

Mice

Cyp3a-KO(FVB,2)

Strain Name：FVB-Cyp3a57em2Cyp3a59em2Cyp3a13em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190427

All genes between Cyp3a57 and Cyp3a59 (including Cyp3a11, Cyp3a16, Cyp3a25, Cyp3a41, Cyp3a44, Cyp3a57, Cyp3a58-ps, Cyp3a59) and Cyp3a13 were knocked out to generate Cyp3a-KO(FVB,2) mice (Stock No.NM-KO-190427).All genes between Cyp3a57 and Cyp3a59 (including Cyp3a11, Cyp3a16, Cyp3a25, Cyp3a41, Cyp3a44, Cyp3a57, Cyp3a58-ps, Cyp3a59) were knocked out to generate Cyp3a-KO(FVB) mice (Stock No.NM-KO-18056).

Mice

Igl-KO

Strain Name：C57BL/6Smoc-Iglem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191198

All genes between Gm10088 and Iglv2 were deleted to generate Igl knockout mice.

Mice

hTRBC1/hTRBC2

Strain Name：C57BL/6Smoc-Trbc1tm1(hTRBC1)Trbc2tm1(hTRBC2)Smoc
Strain State：Developing | Cat. NO.：NM-HU-242618

The endogenous mouse Trbc1 and Trbc2 gene was replaced by human TRBC1 and TRBC2 gene.

Mice

hHBB

Strain Name：C57BL/6Smoc-Hbb-bt&Hbb-bstm1(hHBB)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000080

The endogenous mouse Hbb-bt and Hbb-bs gene was replaced by human HBB gene.

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