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Models

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Literature

Raloxifene inhibits bone loss and improves bone strength through an Opg-independent mechanism

Model Organisms:小鼠 Product & Service:Opg Research field:Skeleton

药物作用机制

Literature

CRISPR/Cas9‑mediated somatic and germline gene correction to restore hemostasis in hemophilia B mice

Model Organisms:Mouse Product & Service:F9 Research field:Hemophilia

Literature

Necdin regulates BMAL1 stability and circadian clock through SGT1-HSP90 chaperone machinery

Model Organisms:Mouse Product & Service:Ndn Research field:Circadian clocks

Literature

ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells

Model Organisms:小鼠 Product & Service:Zfp91-floxed Research field:T cell

Literature

Thrombin cleaves IL-33 and modulates IL-33-activated allergic lung inflammation

Model Organisms:小鼠 Product & Service:Il33-KO Research field:Immunology

Literature

Mydgf promotes Cardiomyocyte proliferation and Neonatal Heart regeneration

Model Organisms:小鼠 Product & Service:Mydgf-flox Research field:myocardial regeneration

Literature

METTL14 aggravates podocyte injury and glomerulopathy progression through N6-methyladenosine-dependent downregulating...

Model Organisms:小鼠 Product & Service:Mettl14-Flox Research field:podocyte injury and glomerulopathy

Literature

LARP7 ameliorates cellular senescence and aging by allosterically enhancing SIRT1 deacetylase activity

Model Organisms:小鼠 Product & Service:Apoe-KO(2) Research field:衰老

Literature

Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice

Model Organisms:小鼠 Product & Service:Shox2 Research field:Development

骨骼 成骨分化 Wnt1-Cre

Literature

Apj+ Vessels Drive Tumor Growth and Represent a Tractable Therapeutic Target

Model Organisms:Mouse Product & Service:APJ-CreER,Apj-DTRGFP-Luc Research field:Genetic lineage tracing

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