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Models

About 1,066 results
Mice

hOX40(2)

Strain Name：C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00078

The exon1-5 and partial exon6 of endogenous mouse Tnfrsf4(Ox40) gene was replaced by the corresponding region of human TNFRSF4(OX40) gene. While hOX40(Stock No.NM-HU-00041) mice function similarly to hOX40(2) mice,for more detailed information please contact our technical advisor.

Mice

Mycn-TRE-EGFP

Strain Name：B6;129S-Mycntm1(TRE-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00008

A TRE site and a loxp EGFP casette were inserted into introns 1-2 to create a Dox-inducible N-myc gene silence mice.

Mice

Pnpla3-KO

Strain Name：B6;129S-Pnpla3tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00051

Exons 1-3 and partial exon 4 were replaced by Neo cassette.

Mice

hC5AR1/C5AR2

Strain Name：C57BL/6Smoc-C5ar1tm1(hC5AR1)C5ar2tm1(hC5AR2)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000018

The endogenous mouse C5ar1 and C5ar2 gene was replaced by human C5AR1 and hC5AR2 gene.

Mice

Igl-KO

Strain Name：C57BL/6Smoc-Iglem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-191198

All genes between Gm10088 and Iglv2 were deleted to generate Igl knockout mice.

Mice

hCSF1/hCSF1R(BALB/c)

Strain Name：BALB/cAnSmoc-Csf1tm2(CSF1)Csf1rem3(hCSF1R)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220016

The endogenous mouse Csf1 and Csf1r genes was replaced respectively by human CSF1 and CSF1R genes.

Mice

hIL2/hIL2RA(BALB/c)

Strain Name：BALB/cAnSmoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220018

The endogenous mouse Il2 and Il2ra gene was replaced respectively by human IL2 and IL2RA gene.

Mice

hOX40/hCTLA-4

Strain Name：C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4)Ctla4em1(hCTLA4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00105

These mice are OX40 and CTLA4 double knockin mouse models which can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hIL3/hCSF2

Strain Name：C57BL/6Smoc-Il3tm3(hIL3)Csf2tm3(hCSF2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190065

The endogenous mouse Il3 and Csf2 gene was replaced by human IL3 and CSF2 gene.

Mice

hIL5/hIL5R(2)

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Il5raem2(hIL5RA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220010

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(3)(Stock No.NM-HU-220011) function similarly to hIL5/hIL5R(2) mice, for more detailed information please contact our technical advisor.

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