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Models

About 1,041 results
Mice

Slco1b2\Slco1a5-KO

Strain Name：C57BL/6Smoc-Slco1b2em1Slco1a5em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-18030
Validation Data：Presence

Slco1b2 and Slco1a5 were removed in this strain.

Mice

Mir183/Mir96-KO

Strain Name：C57BL/6Smoc-Mir183emMir96em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-234774

Mir183 and Mir96 knockout mouse models were established by knockout transcripts of Mir183-201 and Mir96-201.

Mice

Igk/Igl-KO

Strain Name：C57BL/6Smoc-IgkemIglem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-241950

Igk and Igl genes were deleted to generate Igk/Igl knockout mice.

Mice

Rag2/IL2rg-KO/hCD40

Strain Name：C57BL/6Smoc-Cd40tm1(hCD40)Rag2em1Il2rgem1Smoc
Strain State：Developing | Cat. NO.：NM-HU-2000112

The Rag2 and Il2rg genes of the CD40 humanized mouse were deleted.

Mice

Rag2/IL2rg-KO/hSIRPA(2)/hCD47

Strain Name：C57BL/6Smoc-Rag2em1Il2rgem1Sirpatm1(hSIRPA)Cd47tm1(hCD47)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000019

The Rag2 and Il2rg genes of the hSIRPA(2)/hCD47 mouse were deleted.

Mice

hCD19/hCD3E

Strain Name：C57BL/6Smoc-Cd19tm1(hCD19)Cd3etm1(hCD3E)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190027
Validation Data：Presence

This CD19 and CD3E double knockin strain is established by crossing CD19-HU and CD3E-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hTLR9/hOX40

Strain Name：C57BL/6Smoc-Tlr9tm1(hTLR9)Tnfrsf4tm3(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190024

This TLR9 and OX40 double knockin strain is established by crossing TLR9-HU and OX40-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hIL6/hIL6R

Strain Name：C57BL/6Smoc-Il6tm1(hIL6)Il6ratm1(hIL6R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190025
Validation Data：Presence

This IL6 and IL6R double knockin strain is established by crossing IL6-HU and IL6R-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hICOS/hICOSL

Strain Name：C57BL/6Smoc-Icosltm1(hICOSLG) Icostm1(hICOS)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18018
Validation Data：Presence

This ICOS and ICOSL double knockin strain is established by crossing ICOS-HU and ICOSL-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hSIRPA(2)/hCD47

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000111
Validation Data：Presence

This SIRPA and CD47 double Knock-in strain is established by crossing hSIRPA and hCD47 mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.While hSIRPA/hCD47 (Stock No.NM-HU-190019) have been pulled from shelves for some reasons.

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