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Models

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Mice

R26-CAG-EGFP(2)

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-EGFP-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190089

These mice harbor a CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus.1 generated by homologous recombination. While R26-CAG-EGFP(Stock No.NM-KI-190088) and R26-CAG-EGFP(3)(Stock No.NM-KI-190090) function similarly to R26-CAG-EGFP(2) mice,for more detailed information please contact our technical advisor.

Mice

R26-CAG-LSL-hFGFR2-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-FGFR2-luciferase-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190007

A SA-2xpolyA-CAG-LSL-FGFR2-IRES-luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the FGFR2 protein.

Mice

R26-CAG-EGFP(3)

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem2(CAG-EGFP-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190090

These mice harbor a CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus.2 generated by homologous recombination. While R26-CAG-EGFP(Stock No.NM-KI-190088) and R26-CAG-EGFP(2)(Stock No.NM-KI-190089) function similarly to R26-CAG-EGFP(3) mice,for more detailed information please contact our technical advisor.

Mice

Dsg1b-Flox

Strain Name：C57BL/6Smoc-Dsg1bem1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-252691

These mice carry loxP sites flanking exon 2-5 of Dsg1b gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dsg1b gene.The Dsg1a gene exhibits high similarity to the Dsg1b and Dsg1c genes, which may interfere with the detection of their mRNA and protein.

Mice

R26-CAG-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpA-CAG-EGFP-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190088

These mice harbor a SA-2xpA-CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. While R26-CAG-EGFP(2)(Stock No.NM-KI-190089) and R26-CAG-EGFP(3)(Stock No.NM-KI-190090) function similarly to R26-CAG-EGFP mice,for more detailed information please contact our technical advisor.

Mice

Cdkn2a/Cdkn2b-Flox(p15/p16-Flox)

Strain Name：C57BL/6Smoc-Cdkn2a/Cdkn2bem2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-250099

On the basis of Cdkn2b-Flox(NM-CKO-2115067), a p15/ P16-Flox mouse model was obtained by inserting loxP on both sides of Cdkn2b(p15) gene exon 2 and lox2272 on both sides of Cdkn2a(p16) gene exon1. The flox region of these strains is exon2 of p15 gene and exon1 of p16 gene.

Mice

Pax7-IRES-Cre

Strain Name：C57BL/6Smoc-Pax7em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200120

A IRES-iCre expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7.

Mice

Pax7-IRES-CreERT2

Strain Name：C57BL/6Smoc-Pax7em1(IRES-Cre-ERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200099

A IRES-Cre-ERT2 expression cassette was knocked into the Pax7 gene stop codon site. Pax7 is expressed in myogenic progenitor cells. Pax7 is essential for the myogenic potential, survival, and proliferation of myogenic progenitors. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Pax7 after tamoxifen treatment.

Mice

Notch1-CreERT2

Strain Name：C57BL/6Smoc-Notch1em1(CreERT2-2xpA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200122

A CreERT2-2xpA expression cassette was knocked into the Notch1 gene start codon site. Notch1 performs vital cell functions, such as proliferation, differentiation, apoptosis, and stem cell maintenance. When Notch1-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in NOTCH1 positive cells.

Mice

Tcrα/Tcrβ/Tcrg-KO

Strain Name：C57BL/6Smoc-TcrαemTcrβemTcrgemSmoc
Strain State：Repository Live | Cat. NO.：NM-XA-241756

The Tcrα-KO(2)(NM-KO-230149) was crossed with Tcrβ-KO(2)(NM-KO-230150) and Tcrg-KO(NM-KO-230157) to generate Tcrα/Tcrβ/Tcrg-KO mice.

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