Welcome to Advanced Search

Models

About 1,068 results
Mice

Cd8a-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Cd8aem1(V5-IRES-luci-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18030

A V5-IRES-luci-2A-EGFP expression cassette was inserted before the stop codon TAA of mouse Cd8a gene to establish a multi-labeled knockin model with V5, luciferase and EGFP fluorescent protein.

Mice

hTNFR2/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220041

hTNFRSF1B(NM-HU-190010)，hPD-1(NM-HU-00015) and hPD-L1(NM-HU-00062) were crossed together to generate hTNFRSF1B/hPD-1/hPD-L1 mice.

Mice

hLAIR1/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Lair1em2(LAIR1)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220040

hLAIR1(NM-HU-2000011)，hPD-1(NM-HU-00015) and hPD-L1(NM-HU-00062) were crossed tegother to generate hLAIR1/hPD-1/hPD-L1 mouse.

Mice

hFCRN(3)

Strain Name：C57BL/6Smoc-Fcgrttm3(hFCGRT)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000032

The endogenous mouse Fcgrt gene was replaced by human FCGRT gene. While hFCRN(Stock No.NM-HU-00109）and hFCRN(2)(Stock No.NM-HU-190070) mice function similarly to hFCRN(3) mice,for more detailed information please contact our technical advisor.

Mice

R26-CAG-LSL-Luc-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-luci-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18051

A CAG-loxP STOP-loxP-luci-2A-tdTomato-WPRE-polyA cassette was knocked into the mouse ROSA26 locus . This strain of mice can be mated with mice expressing Cre recombinase so that luciferase and tdTomato fluorescent protein could be expressed for cell tracing.

Mice

Prom1-CreERT2

Strain Name：C57BL/6Smoc-Prom1em1(CreERT2-PolyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200169

A CreERT2-PolyA expression cassette was knocked into the Prom1 gene start codon site. Prom1 encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. When these Prom1-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Prom1 expressing cells.

Mice

Prl-IRES-CreERT2

Strain Name：C57BL/6Smoc-Prlem1(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200170

A IRES-CreERT2 expression cassette was knocked into the Prl gene stop codon site. Prolactin (PRL) is a hormone synthesized and secreted by lactotroph cells in the anterior pituitary gland. PRL is responsible for lactogenesis and other processes associated with it. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre.

Mice

a-IRES-Cre

Strain Name：C57BL/6Smoc-atm1(Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200027

A IRES-Cre expression cassette was knocked into the a gene stop codon site via ESC targeting. Male mice with a germline Cre leak expression condition, please use female mice and flox mice for breeding crosses. References are available, please see the website for details.

Mice

Wnt1-Dre

Strain Name：C57BL/6Smoc-Wnt1em1(Dre-Wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200176

A Dre-Wpre-polyA expression cassette was knocked into the Wnt1 gene start codon site. Wnt1 gene is involved in stem cell poliferation in multiple systems, including the hematopoietic system and the embryonic nervous system. This strain may be useful for studying central nervous system development. When crossed with a strain carrying a gene flanked by rox sites, the flanked gene will be removed in cells expressing dre.

Mice

hSIRPA(2)/hCD47/hPD-1/hPD-L1(2)

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em2(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220029

hSIRPA(2)(NM-HU-18015), hCD47(NM-HU-00050) and hPD-1(NM-HU-00015) was crossed with hPD-L1(2)(NM-HU-190039）to generate hSIRPA(2)/hCD47/hPD-1/hPD-L1(2) mice.

Email Back to top