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Models

About 1,066 results
Mice

H2-D1/H2-K1/MHCII-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1h2em1H2-D1emH2-K1em1Smoc
Strain State：Developing | Cat. NO.：NM-KO-241515

On the basis of NM-NSG-006 strain, the exon 1-9 of H2-D1 and exon 1-6 of H2-K1 genes were deleted to generate H2-D1 and H2-K1 knockout mouse.

Mice

Hbb-bs/Hbb-bt-KO

Strain Name：C57BL/6Smoc-Hbb-bsemHbb-btem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-234923

The 5' upstream sequence of Hbb-bs gene to the 3' downstream sequence of Hbb-bt gene were deleted to generate Hbb-bs and Hbb-bt knockout mouse.

Mice

BALB/c

Strain Name：BALB/cAnSmoc
Strain State：Repository Live | Cat. NO.：SM-003

BALB/c is one of the most widely used inbred lines in biomedical research, especially in immunology and infectious disease research. The incidence of breast tumors is about 10% to 20%. There is a certain number of ovarian, adrenal, pulmonary tumors, and leukemia that occurs. Lung cancer occurs in 26% of female mice and 29% of male mice. The incidence of leukemia is 12% in females and 10% in males. Blood pressure was the highest compared to other inbred mice and had spontaneous hypertension.

Mice

R26-CAG-Cas9

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-Cas9)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00120

These mice were established by crossing R26-(CAG-LSL-Cas9) and EIIA mice together.

Mice

hIL23A(DBA/1)

Strain Name：DBA/1-Il23aem3(hIL23A)Smoc
Strain State：Developing | Cat. NO.：NM-HU-240255

Strain derived from the backcross of hIL23A(NM-HU-18030)mice and DBA/1 mice.

Mice

hIL6/hIL6R(DBA/1)

Strain Name：DBA/1-Il6tm1(hIL6)Il6raem1(hIL6R)Smoc
Strain State：Developing | Cat. NO.：NM-HU-240241

Strain derived from the backcross of hIL6/hIL6R(NM-HU-190025) and DBA/1 mice.

Mice

Trpv2-Flox

Strain Name：B6;129S-Trpv2tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00023

Mice homozygous for a knock-out allele exhibit impaired macrophage migration, binding, and phagocytosis with increased susceptiblity and mortality following bacterial infection.

Mice

hIL17A/hIL17F(DBA/1)

Strain Name：DBA/1-Il17atm1(hIL17A)Il17fem2(hIL17F)Smoc
Strain State：Developing | Cat. NO.：NM-HU-240220

Strain derived from the backcross of hIL17A/hIL17F(NM-HU-200281)mice and DBA/1 mice.

Mice

hTNFa-Tg(DBA/1)

Strain Name：DBA/1-Tgtn(hTNFa promoter-hTNFa-pA)Smoc
Strain State：Developing | Cat. NO.：NM-TG-240240

Strain derived from the backcross of hTNFa-Tg(NM-TG-200004)mice and DBA/1 mice.

Mice

Rag2-KO

Strain Name：C57BL/6Smoc-Rag2em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190429

Partial exon 3 of Rag2 gene was deleted to generate Rag2 knockout mice. Deletion of this region will cause frameshift and result in loss of function of mouse Rag2 gene.

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