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Models

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Mice

Sprr2a-KO

Strain Name：C57BL/6Smoc-Sprr2a1emSprr2a2emSprr2a3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-241703

The exon 1-exon 2 of Sprr2a1, exon 1-exon 2 of Sprr2a2 and exon 1-exon 2 of Sprr2a3 genes were deleted to generate Sprr2a1, Sprr2a2 and Sprr2a3 knockout mouse.

Mice

Cdkn2a/Cdkn2b-KO(p15/p16/p19-KO)

Strain Name：C57BL/6Smoc-Cdkn2aemCdkn2bem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-241617

The p15/p16/p19-KO mouse model was established by knocking out all genomic regions between exon1 of the p15 gene and exon1 of the p16 gene.

Mice

Cdkn2a/Cdkn2b-Flox(p15/p16/p19-Flox)

Strain Name：C57BL/6Smoc-Cdkn2a/Cdkn2bem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-235093

The p15/p16/p19-Flox mouse model was obtained by inserting a loxp site upstream of the Cdkn2b gene exon 1 and another loxP site downstream of the Cdkn2a(p16) gene exon 1. The flox region of these strains contains the entire genomic region between exon1 of the p15 gene and exon1 of the p16 gene.

Mice

Clec18a-Flox

Strain Name：B6;129S-Clec18atm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00006

These mice possess loxP sites on either side of exon 5 of C-type lectin domain family 18 member A gene and followed by an frt-neo-frt cassette. When crossed with a Cre recombinase-expressing strain,this strain is useful in eliminating tissue-specific con

Mice

H2-D1/H2-K1/MHCII-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1h2em1H2-D1emH2-K1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-241515

On the basis of NNMG-006 strain, the exon 1-9 of H2-D1 and exon 1-6 of H2-K1 genes were deleted to generate H2-D1 and H2-K1 knockout mouse.

Mice

IL1B-Luc-Tg

Strain Name：B6.Cg-Tg(IL1B-Luc)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-TG-00001
Validation Data：Presence  |  Publications：1piece

The transgenic mice model could be used to study transcriptional regulation of the IL-1βgene expression in the inflammatory process and evaluation the effect of anti-inflammatory drug in vivo.

Mice

Hbb-bs/Hbb-bt-KO

Strain Name：C57BL/6Smoc-Hbb-bsemHbb-btem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-234923

The 5' upstream sequence of Hbb-bs gene to the 3' downstream sequence of Hbb-bt gene were deleted to generate Hbb-bs and Hbb-bt knockout mouse.

Mice

R26-CAG-Cas9

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-Cas9)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00120
Validation Data：Presence

These mice were established by crossing R26-(CAG-LSL-Cas9) and EIIA mice together.

Mice

BALB/c

Strain Name：BALB/cAnSmoc
Strain State：Repository Live | Cat. NO.：SM-003

BALB/c is one of the most widely used inbred lines in biomedical research, especially in immunology and infectious disease research. The incidence of breast tumors is about 10% to 20%. There is a certain number of ovarian, adrenal, pulmonary tumors, and leukemia that occurs. Lung cancer occurs in 26% of female mice and 29% of male mice. The incidence of leukemia is 12% in females and 10% in males. Blood pressure was the highest compared to other inbred mice and had spontaneous hypertension.

Mice

hTIGIT/hPVR

Strain Name：C57BL/6Smoc-Tigittm1(hTIGIT)Pvrtm1(hPVR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000091
Validation Data：Presence

These mice are obtained through breeding of hTIGIT(NM-HU-00053) and hPVR(NM-HU-190012) mice.

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