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Models

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Mice

Cdkn2a/Cdkn2b-Flox(p15/p16/p19-Flox)

Strain Name：C57BL/6Smoc-Cdkn2a/Cdkn2bem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-235093

The p15/p16/p19-Flox mouse model was obtained by inserting a loxp site upstream of the Cdkn2b gene exon 1 and another loxP site downstream of the Cdkn2a(p16) gene exon 1. The flox region of these strains contains the entire genomic region between exon1 of the p15 gene and exon1 of the p16 gene.

Mice

H2-D1/H2-K1/MHCII-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1h2em1H2-D1emH2-K1em1Smoc
Strain State：Developing | Cat. NO.：NM-KO-241515

On the basis of NM-NSG-006 strain, the exon 1-9 of H2-D1 and exon 1-6 of H2-K1 genes were deleted to generate H2-D1 and H2-K1 knockout mouse.

Mice

Il1b-Luc-Tg

Strain Name：B6.Cg-Tg(IL1B-luc)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-00001

The transgenic mice model could be used to study transcriptional regulation of the IL-1βgene expression in the inflammatory process and evaluation the effect of anti-inflammatory drug in vivo.

Mice

Hbb-bs/Hbb-bt-KO

Strain Name：C57BL/6Smoc-Hbb-bsemHbb-btem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-234923

The 5' upstream sequence of Hbb-bs gene to the 3' downstream sequence of Hbb-bt gene were deleted to generate Hbb-bs and Hbb-bt knockout mouse.

Mice

BALB/c

Strain Name：BALB/cAnSmoc
Strain State：Repository Live | Cat. NO.：SM-003

BALB/c is one of the most widely used inbred lines in biomedical research, especially in immunology and infectious disease research. The incidence of breast tumors is about 10% to 20%. There is a certain number of ovarian, adrenal, pulmonary tumors, and leukemia that occurs. Lung cancer occurs in 26% of female mice and 29% of male mice. The incidence of leukemia is 12% in females and 10% in males. Blood pressure was the highest compared to other inbred mice and had spontaneous hypertension.

Mice

R26-CAG-Cas9

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-Cas9)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00120

These mice were established by crossing R26-(CAG-LSL-Cas9) and EIIA mice together.

Mice

hIL6/hIL6R(DBA/1)

Strain Name：DBA/1-Il6tm1(hIL6)Il6raem1(hIL6R)Smoc
Strain State：Developing | Cat. NO.：NM-HU-240241

Strain derived from the backcross of hIL6/hIL6R(NM-HU-190025) and DBA/1 mice.

Mice

hTIGIT/hPVR

Strain Name：C57BL/6Smoc-Tigitem1(hTIGIT)Pvrem1(hPVR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000091

These mice are obtained through breeding of hTIGIT(NM-HU-00053) and hPVR(NM-HU-190012) mice.

Mice

hIL23A(DBA/1)

Strain Name：DBA/1-Il23aem3(hIL23A)Smoc
Strain State：Developing | Cat. NO.：NM-HU-240255

Strain derived from the backcross of hIL23A(NM-HU-18030)mice and DBA/1 mice.

Mice

hIL17A/hIL17F(DBA/1)

Strain Name：DBA/1-Il17atm1(hIL17A)Il17fem2(hIL17F)Smoc
Strain State：Developing | Cat. NO.：NM-HU-240220

Strain derived from the backcross of hIL17A/hIL17F(NM-HU-200281)mice and DBA/1 mice.

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