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Models

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Mice

BC028528-Flox

Strain Name：B6;129S-BC028528tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00012

An frt-neo-frt cassette was inserted before exon 3. And these mice possess loxP sites on either side of exon 3. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

hSIRPA/hCD47(BALB/c)

Strain Name：BALB/cAnSmoc-Sirpatm4(hSIRPA)/SmocCd47em1(hCD47)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210020

hCD47 (NM-HU-00050) and hSRPA(2)(NM-HU-18015) were bred with BALB/c mice respectively to generate hSIRPA/hCD47(BALB/c) mice.

Mice

hIL2/hIL2RB/hIL2RG

Strain Name：C57BL/6Smoc-Il2rgem1(IL2RG)Il2tm3(hIL2)Il2rbtm1(hIL2RB)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220145

hIL2RG(NM-HU-200007) and IL2RB(NM-HU-2000055) mice were crossed with hIL2(NM-HU-190048) mice to generate hIL2/hIL2RB/hIL2RG mice.

Mice

hGDF15/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Gdf15em1(hGDF15)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220151

hGDF15(NM-HU-215002) and hPD-1(NM-HU-00015)mice were crossed with hPD-L1(NM-HU-00062) mice to generate hIL2/hIL2RB/hIL2RG mice.

Mice

hPD-1/hPD-L1(2)/hCCR8

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em2(hPD-L1)Ccr8em1(hCCR8)/Smoc
Strain State：Developing | Cat. NO.：NM-HU-210402

hPD-1(NM-HU-00015) and hPD-1(2)(NM-HU-190039) were crossed with hCCR8(NM-HU-190053) to generate hPD-1/hPD-L1(2)/hCCR8 mice.

Mice

IgI/Ighj/Igkj-KO

Strain Name：C57BL/6Smoc-Iglem1Ighjem1Igkjem1/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210395

Igl-KO(NM-KO-191198) and Igkj-KO(NM-KO-191196) were crossed with Ighj-KO(NM-KO-191197) to generate IgI/Ighj/Igkj-KO mice.

Mice

Sprr2a-KO

Strain Name：C57BL/6Smoc-Sprr2a1emSprr2a2emSprr2a3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-241703

The exon 1-exon 2 of Sprr2a1, exon 1-exon 2 of Sprr2a2 and exon 1-exon 2 of Sprr2a3 genes were deleted to generate Sprr2a1, Sprr2a2 and Sprr2a3 knockout mouse.

Mice

Il18-3×FLAG-NLS-mNeongreen-NLS-6×HIS

Strain Name：C57BL/6Smoc-Il18em1(3×FLAG-NLS-mNeongreen-NLS-6×HIS)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-233874

The 3×FLAG-NLS-mNeongreen-NLS-6×HIS expression cassette was substituted for the sequence between the start and stop codons of the Il18 gene.

Mice

Clec18a-Flox

Strain Name：B6;129S-Clec18atm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00006

These mice possess loxP sites on either side of exon 5 of C-type lectin domain family 18 member A gene and followed by an frt-neo-frt cassette. When crossed with a Cre recombinase-expressing strain,this strain is useful in eliminating tissue-specific con

Mice

Cdkn2a/Cdkn2b-KO(p15/p16/p19-KO)

Strain Name：C57BL/6Smoc-Cdkn2aemCdkn2bem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-241617

The p15/p16/p19-KO mouse model was established by knocking out all genomic regions between exon1 of the p15 gene and exon1 of the p16 gene.

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