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Models

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Mice

Tnfrsf1a/Tnfrsf1b-KO

Strain Name：C57BL/6Smoc-Tnfrsf1aem1Tnfrsf1bem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18036

This strain is also called p55/p75-KO. The Tnfrsf1a and Tnfrsf1b double knockout mouse models were obtained by knocking out both exon 2-5 region of mouse Tnfrsf1a gene and exon2 of mouse Tnfrsf1b gene. Tnfrsf1a and Tnfrsf1b deletion (p55 and p75 deficiency) homozygous mice are viable and fertile, and these homozygous mice fail to bind TNF (tumor necrosis factor).

Mice

BC028528-Flox

Strain Name：B6;129S-BC028528tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00012

An frt-neo-frt cassette was inserted before exon 3. And these mice possess loxP sites on either side of exon 3. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Gstp1/Gstp2/Gstp3-KO

Strain Name：C57BL/6Smoc-Gstp1/Gstp2/Gstp3em/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-220477

The Gstp1，Gstp2，and Gstp3 gene were deleted to generate Gstp1,Gstp2,Gstp3 knockout mice.

Mice

hCD98(V1)

Strain Name：C57BL/6Smoc-Slc3a2tm1(hSLC3A2)Smoc
Strain State：Developing | Cat. NO.：NM-HU-253946

The endogenous mouse Slc3a2 gene was replaced by human SLC3A2 gene.This strain contains a humanized 3'UTR and can be used for small nucleic acid drug research.

Mice

hSIRPA/hCD47(BALB/c)

Strain Name：BALB/cAnSmoc-Sirpatm4(hSIRPA)SmocCd47tm1(hCD47)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210020
Validation Data：Presence

hCD47 (NM-HU-00050) and hSRPA(2)(NM-HU-18015) were bred with BALB/c mice respectively to generate hSIRPA/hCD47(BALB/c) mice.

Mice

hGDF15/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Gdf15tm1(hGDF15)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220151

hGDF15(NM-HU-215002) and hPD-1(NM-HU-00015)mice were crossed with hPD-L1(NM-HU-00062) mice to generate hIL2/hIL2RB/hIL2RG mice.

Mice

hIL2/hIL2RB/hIL2RG

Strain Name：C57BL/6Smoc-Il2rgtm1(IL2RG)Il2tm3(hIL2)Il2rbtm1(hIL2RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220145

hIL2RG(NM-HU-200007) and IL2RB(NM-HU-2000055) mice were crossed with hIL2(NM-HU-190048) mice to generate hIL2/hIL2RB/hIL2RG mice.

Mice

hPD-1/hPD-L1(2)/hCCR8

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd274tm2(hPD-L1)Ccr8tm1(hCCR8)/Smoc
Strain State：Developing | Cat. NO.：NM-HU-210402

hPD-1(NM-HU-00015) and hPD-1(2)(NM-HU-190039) were crossed with hCCR8(NM-HU-190053) to generate hPD-1/hPD-L1(2)/hCCR8 mice.

Mice

IgI/Ighj/Igkj-KO

Strain Name：C57BL/6Smoc-Iglem1Ighjem1Igkjem1/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210395
Validation Data：Presence

Igl-KO(NM-KO-191198) and Igkj-KO(NM-KO-191196) were crossed with Ighj-KO(NM-KO-191197) to generate IgI/Ighj/Igkj-KO mice.

Mice

Il18-3×FLAG-NLS-mNeongreen-NLS-6×HIS

Strain Name：C57BL/6Smoc-Il18em1(3×FLAG-NLS-mNeongreen-NLS-6×HIS)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-233874

The 3×FLAG-NLS-mNeongreen-NLS-6×HIS expression cassette was substituted for the sequence between the start and stop codons of the Il18 gene.

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